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Table 1 Baseline characteristics of 60 children with AHOM

From: Efficacy and safety of vancomycin-loaded calcium sulfate versus conventional surgical debridement for pediatric acute osteomyelitis: a retrospective study

Characteristic

Conventional Group (n = 28)

Vancomycin Group (n = 32)

P-value

Age of onset (years)

3.5 ± 3.8

4.7 ± 3.4

0.118

Male/female, n (%)

19 (67.9)/9 (32.1)

14 (43.8)/18 (56.2)

0.061

CRP at baseline (mg/L)

76.6 ± 38.4 (21.2-161.2)

105.0 ± 57.2 (17.7-275.6)

0.030

WBC at baseline (x109/L)

17.4 ± 8.0 (9.5–41.4)

17.7 ± 7.7 (9.9–41.7)

0.881

ESR at baseline (mm/h)

69.4 ± 25.9 (28–110)

81.0 ± 31.2 (24–130)

0.117

Region of osteomyelitis, n (%)

  

0.329*

 Tibia

2 (7.1)

10 (31.3)

 

 Femur

21 (75)

19 (59.4)

 

 Humerus

5 (17.9)

1 (3.1)

 

 Clavicle

0 (0.0)

1 (3.1)

 

 Radius

0 (0.0)

1 (3.1)

 

Pathogen, n (%)

  

0.152**

 MSSA

10 (35.7)

15 (46.9)

 

 MRSA

5 (17.9)

10 (31.3)

 

Streptococcus pneumoniae

3 (10.7)

2 (6.2)

 

 Other

4 (14.3)

0 (0)

 

 N/A

6 (21.4)

5 (15.6)

 
  1. *Chi-square comparison between infections in the femur versus other regions; **Chi-square comparison between MRSA, MSSA, other bacteria and unculturable bacteria; MRSA methicillin-resistant Staphylococcus aureus, MSSA methicillin-sensitive S aureus