Table 1 Predictors of knee osteoarthritis for model 1 (patient- and laboratory-related factors) and model 2 (laboratory-related factors)

Patient-related risk factors

 Age

1.02 (1.01 – 1.03)

 < 0.001**

 Sex

  Female

0.86 (0.60 – 1.25)

0.444

  Male

—

—

 BMI

1.00 (0.98 – 1.02)

0.808

Laboratory-related risk factors

 POSTN

1.00 (1.00 – 1.00)

0.910

1.00 (1.00 – 1.00)

0.440

 CRP (mg/L)

1.01 (0.99 – 1.02)

0.569

1.00 (0.98 – 1.02)

0.961

 ESR (mm/H)

1.00 (0.98 – 1.01)

0.720

0.99 (0.97 – 1.01)

0.317

 WBC

1.05 (0.95 – 1.15)

0.345

1.04 (0.90–1.19)

0.601

 Neu (%)

0.99 (0.98 – 1.01)

0.442

0.99 (0.97 – 1.01)

0.395

 Hb

1.00 (0.99 – 1.01)

0.991

1.00 (0.98 – 1.01)

0.763

 PLT

1.00 (1.00 – 1.00)

0.808

1.00 (0.99 – 1.00)

0.218

 TP

1.00 (0.96 – 1.05)

0.937

1.04 (0.98 – 1.11)

0.210

 ALB (g/L)

0.99 (0.93 – 1.06)

0.807

0.93 (0.85 – 1.02)

0.151

 ALT (U/L)

1.00 (0.98 – 1.02)

0.839

0.99 (0.96 – 1.01)

0.275

 AST (U/L)

1.00 (0.98 – 1.03)

0.763

1.01 (0.97 – 1.05)

0.594

 Cr (mmol/L)

1.00 (1.00 – 1.00)

0.555

1.00 (1.00 – 1.00)

0.633

 PT (S)

1.04 (0.86 – 1.26)

0.677

1.05 (0.81 – 1.37)

0.717

 INR

1.03 (0.96 – 1.10)

0.450

1.03 (0.93 – 1.14)

0.571

 APTT (S)

1.03 (0.97 – 1.10)

0.289

1.03 (0.95 – 1.12)

0.504

 FIB

1.00 (1.00 – 1.00)

0.531

1.00 (1.00 – 1.01)

0.088

 TT

0.99 (0.98 – 1.00)

0.227

1.00 (0.98 – 1.01)

0.587

 FDP

0.96 (0.82 – 1.12)

0.618

0.90 (0.72 – 1.13)

0.365

 D-dimer

1.00 (1.00 – 1.00)

0.650

1.00 (1.00 – 1.00)

0.388