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Fig. 4 | BMC Musculoskeletal Disorders

Fig. 4

From: Massive foreign body reaction and osteolysis following primary anterior cruciate ligament reconstruction with the ligament augmentation and reconstruction system (LARS): a case report with histopathological and physicochemical analysis

Fig. 4

A, polarized light microscopy (10X) showing bi-refractive PET on a black background of non-refractive tissue. Scale bar = 250 μm. B-C, H&E staining. Bundles of PET surrounded by reactive fibrosis and chronic inflammation with giant multinucleated cells (B, 10x). Scale bar = 250 μm. PET bundle approached by a group of giant multinucleated cells (C, 40x). Scale bar = 50 μm. D-E, Sirius Red staining. Positive staining in fibrous tissue (internal control) and negative stain in bi-refractive extra- and intra-cellular bundles and fibers (yellow arrows). D, 10x magnification, scale bar = 250 μm. E, 40x magnification, scale bar = 50 μm. Yellow arrows indicate PET fibers. The red arrow indicates giant multinucleated cells

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