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Table 1 The 2018 International Consensus Meeting (ICM) definition of PJI

From: Decreased serum superoxide dismutase concentration has a high value for the diagnosis of periprosthetic joint infection—a single-center, retrospective study

Major Criteria

 

Diagnosis

Two positive cultures of the same organism

 

Infected

Sinus tract communicating with the joint or visualization of the implant

 

Minor Criteria (Preoperative Diagnosis)

Score

Diagnosis

Elevated CRP (100 mg /L) or Dimer (860 ng /ml)

2

 ≥ 6 Infected 2–5 Possibly Infected 0–1 Not Infected

Elevated ESR (30 mm /h)

1

Elevated synovial WBC count(3000//μl) or leukocyte esterase (+ +)

3

positive alpha-defensin

3

Elevated synovial PMN percentage (80%)

2

Elevated synovial CRP (6.9 mg /L)

1

Inconclusive pre-op score or dry tap (Intraoperative Diagnosis)

Score

 

Preoperative score

-

 ≥ 6 Infected 4–5 Inconclusive ≤ 3 Not Infected

Positive histology

3

Positive purulence

3

Single positive culture

2

  1. PJI periprosthetic joint infection, CRP C-reactive protein, ESR erythrocyte sedimentation rate, LE leukocyte esterase, PMN polymorphonuclear, WBC white blood cell