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Table 3 Results of multivariate logistic regression analysis of variables associated with recurrent PJI

From: Higher reinfection rate after two-stage revision arthroplasty in patients with refractory diabetes mellitus: a retrospective analysis with a minimum ten-year follow up

Variables

Multivariate model results

Adjusted odds ratio (95% CI)

p

1st Albumin

0.11 (0.04—3.81)

0.342

2nd Albumin

0.13 (0.02—3.21)

0.231

3-stage revision arthroplasty or more

35.02 (1.4—50.63)

 < 0.001*

E. Coli

3.67 (0.19—10.31)

0.22

ESBL-E. Coli

12.33 (1.16—15.55)

 < 0.001*

Fasting glucose, mmol/l

  100 to <  = 200

1.58 (0.19—8.54)

1

  > 200

2.16 (0.22—9.85)

0.64

  1st HbA1c ≥ 7

3.67 (0.21—3.21)

0.32

Last stage HbA1c ≥ 7

28.34 (1.2—40.12)

 < 0.001*

Sulfonylurea (Glipizide, Glimepiride, Gliclazide)

3.21 (0.25—11.24)

0.34

DPP4 inhibitor (Saxagliptin, Linagliptin, Alogliptin, Vildagliptin)

2.58 (0.19—9.32)

0.32

Insulin combined with other OAD Insulin

5.18 (0.28—13.36)

0.12

ACE inhibitor or ARB

0.64 (0.09—8.95)

1

  1. PJI periprosthetic joint infection, E. Coli Escherichia coli, ESBL extended-spectrum beta-lactamases, HbA1c glycohemoglobin, DPP4 Dipeptidyl peptidase 4, OAD oral anti-diabetic drug, ACE angiotensin-converting enzyme, ARB angiotensin II receptor blockers, CI confidence interval
  2. *p value < 0.05