Fig. 5

RORA promotes MSCs chondrogenesis. A Cartilage pellets collected 7 and 14 days after inducing MSCs chondrogenesis. Indicated treatment was added to the culture media. The cartilage pellets were observed with stereoscopic microscope. B The diameter (mm) of cartilage pellet after 7 and 14 days of induced chondrogenesis, 6 pellets were used for measurement in each group. C RT-qPCR analysis was conducted to assess the mRNA expression of COL2A1 and ACAN in chondrocyte pellet with the addition of indicated treatments for 7 days. D RT-qPCR analysis was conducted to assess the mRNA expression of COL2A1 and ACAN in chondrocyte pellet with the addition of indicated treatments for 14 days.* p ≤ 0.05 and ** p ≤ 0.01 compared to the vehicle treated group