| Japan | US | EUR | p-value |
---|---|---|---|---|
 | n = 94 | n = 153 | n = 484 |  |
Lack of mobility | 17 (18%) | 104 (68%) | 258 (53%) |  < 0.001a |
Degree of pain on movement | 49 (52%) | 70 (46%) | 194 (40%) | 0.069a |
Degree of pain at rest | 32 (34%) | 45 (29%) | 220 (45%) |  < 0.001a |
Failure to control condition with drug treatment | 30 (32%) | 54 (35%) | 190 (39%) | 0.332a |
Degree of joint damage | 25 (27%) | 39 (25%) | 151 (31%) | 0.327a |
Patient’s need for independence | 26 (28%) | 36 (24%) | 108 (22%) | 0.530a |
Patient request | 42 (45%) | 30 (20%) | 79 (16%) |  < 0.001a |
X-ray data | 25 (27%) | 25 (16%) | 99 (20%) | 0.151a |
Age of patient | 16 (17%) | 8 (5%) | 49 (10%) | 0.011a |
MRI results | 5 (5%) | 22 (14%) | 42 (9%) | 0.038a |
Patient’s need to continue working | 12 (13%) | 17 (11%) | 38 (8%) | 0.206a |
Patient’s inability to tolerate anti-inflammatories | 3 (3%) | 2 (1%) | 8 (2%) | 0.533b |