Fig. 3
From: Inhibition of SMAD3 effectively reduces ADAMTS-5 expression in the early stages of osteoarthritis
PCR analysis of ADAMTS-5 levels in OA cartilage tissue after intra-articular injection of SIS3 and miRNA-140 mimics. A, B, and C The relative expression levels of ADAMTS-5 in OA cartilage tissue after intra-articular injection of SIS3 at 2, 6, and 12 weeks. (D, E, and F) The relative expression levels of ADAMTS-5 in OA cartilage tissue after intra-articular injection of miRNA-140 mimics at 2, 6, and 12 weeks. *, Compared to the blank group, P < 0.05. **, Compared to the blank group, P < 0.01. ns, Compared to the blank group, P > 0.05