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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Analgesic effects and arthritic changes following intra-articular injection of diclofenac etalhyaluronate in a rat knee osteoarthritis model

Fig. 1

Effect of DF-HA on the pressure withdrawal threshold applied to one posterior ipsilateral limb Changes in hyperalgesia are measured using a von Frey filament and expressed in grams (g) as a 50% paw withdrawal threshold. Behavioral tests are performed before MIA administration (BL). Further, 2 mg of MIA is administered, and the von Frey test is performed weekly for 8 weeks. DF-HA (DF-HA group) or vehicle (vehicle group) is administered at week 4 and FG is administered at week 7 after the test. Lower threshold values indicate enhanced hyperalgesia. Data are expressed as the mean ± standard error of four animals per group

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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