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Table 1 Cases of carpal tunnel syndrome secondary to tumoral calcinosis published in the English literature

From: Carpal tunnel syndrome secondary to tumoral calcinosis: a case report and review of the literature

First author’s name

Year of publication

Age of patient (in years), gender

Past medical history

Diagnostic modality

Size of the tumor in cm

Treatment modality

Histopathological findings

Suggested etiology

Hecht et al.[10]

1980

41, F

None

X-ray of the wrist joint

Not mentioned

Surgical resection

Not mentioned

Not mentioned

De et al.[17]

1983

32, F

None

X-ray of the wrist joint

2.5 Ă— 0.8

Surgical resection

Not mentioned

Primary calcinosis Nonfamilial

Weiber et al.[2]

1987

63, F

None

Only clinical

3 Ă— 1

Surgical resection

Rounded psammoma-like bodies and granulation tissue containing histyocytes and osteoclast-like giant cells

Primary calcinosis Nonfamilial

Ali et al.[18]

1988

41, F

None

X-ray of the wrist joint

Not mentioned

Surgical resection

No true capsule and the mass contains calcium phosphate in a fibrous proliferation, giant cells, and lymphocytes

Primary calcinosis Nonfamilial

Bostrom et al.[19]

1993

38, F

None

X-ray of the wrist joint

Not mentioned

Surgical resection

Not mentioned

Not mentioned

Bostrom et al.[19]

1993

64, F

Hypothyroidism

X-ray of the wrist joint

0.5 Ă— 0.9

Surgical resection

Not mentioned

Not mentioned

Knight et al.[20]

1993

50, F

None

X-ray of the wrist joint

Not mentioned

Surgical resection

Acute inflammatory changes and an area of calcification

Primary calcinosis Nonfamilial

Asami et al.[12]

1998

52, M

ESRD on HD

Electrophysiological study

Large mass (exact size not mentioned)

Surgical resection

Fibrous connective tissue+ calcified area surrounded by mononuclear cells + polynuclear cells with lipi-containing cytoplasm and foreign body giant cells

Secondary: Hyperphosphatemia

Takada et al.[8]

2000

63, F

Not mentioned

Electrophysiological study + X-ray of the wrist joint

2 Ă— 1.2

Surgical resection

Amorphous calcified material encapsulated with fibrous membrane without inflammation

Primary calcinosis Nonfamilial

Cofan et al.[13]

2002

25, F

SLE, ESRD on HD

Electrophysiological study + CT and MRI of the wrist joint

4 Ă— 3.4

Surgical resection + Increase in the duration of dialysis+ correction of the hyperphosphatemia + parathyroidectomy

Calcified mass surrounded by granulation tissue with histyocytes and some multinucleated cells

Secondary: Severe hypercalcemia and hyperphosphataemia from hyperparathyroididsm and excessive calcitriol administration

Sensui et al.[21]

2003

64, F

Not mentioned

Electrophysiological study + CT of the wrist joint

Not mentioned

Surgical resection

Amorphous calcification

Primary calcinosis Nonfamilial

Pai et al.[22]

2009

64, F

None

X-ray and CT of the wrist joint

2 Ă— 2

Surgical resection

Hydroxyapatite crystals

Primary calcinosis Nonfamilial

Kang et al.[23]

2009

55, F

None

CT and MRI of the wrist joint

Not mentioned

Surgical resection

Amorphous calcified material encapsulated with fibrous membrane

Not mentioned

Kang et al.[23]

2009

78, F

None

CT and MRI of the wrist joint

Not mentioned

Surgical resection

Amorphous calcified material encapsulated with fibrous membrane

Not mentioned

Kang et al.[23]

2009

55, F

None

CT and MRI of the wrist joint

Not mentioned

Surgical resection

Amorphous calcified material encapsulated with fibrous membrane

Not mentioned

Inui et al.[4]

2015

54, F

None

Electrophysiological study + CT and MRI of the wrist joint

2.7 Ă— 1.2

Surgical resection

Basophile deposition inside the fibrous connective tissue. Made of 82% calcium phosphate and 17% calcium carbonate

Primary calcinosis Nonfamilial

Kwon et al.[3]

2018

45, F

None

Electrophysiological study + US and MRI of the wrist joint

1.19 Ă— 0.96

Surgical resection

Calcified nodules

Primary calcinosis Nonfamilial

Cheng et al.[24]

2019

57, F

None

X-ray and MRI of the wrist joint

1.3 Ă— 0.8 Ă— 1

Surgical resection

Calcified nodule

Primary calcinosis Nonfamilial

Cheng et al.[24]

2019

52, F

Type 2 diabetes mellitus

Electrophysiological study + X-ray and ultrasound of the wrist joint

0.6 Ă— 0.6 Ă— 1.3

Surgical resection

Calcified nodule

Primary calcinosis Nonfamilial

  1. CT Computerized Tomography, ESRD End-Stage Renal Disease, F Female, HD Hemodialysis, M Male, MRI Magnetic Resonance Imaging, SLE Systemic Lupus Erythematosus, US Ultrasound