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Table 11 Hoffa- and effusion-synovitis – baseline and change over 24 months

From: Structural tissue damage and 24-month progression of semi-quantitative MRI biomarkers of knee osteoarthritis in the IMI-APPROACH cohort

 

All knees

No ROA

ROA

P

Frequency

Percent

Frequency

Percent

Frequency

Percent

 

Baseline

  Hoffa synovitis

0

96

33.4

57

44.2

39

24.7

0.0001

1

143

49.8

60

46.5

83

52.5

2+

48

16.7

12

9.3

36

22.8

  Effusion synovitis

0

155

54.0

101

78.3

54

34.2

0.0000

1

87

30.3

23

17.8

64

40.5

2

33

11.5

1

0.8

32

20.3

3

12

4.2

4

3.1

8

5.1

Change in maximum score by grade

  Hoffa synovitis

-1

16

7.0

6

5.5

10

8.3

0.7526

0

196

85.2

98

89.1

98

81.7

1

17

7.4

5

4.5

12

10.0

2

1

0.4

1

0.9

0

0.0

  Effusion synovitis

-2

1

0.4

1

0.9

0

0.0

0.7947

-1

22

9.6

5

4.5

17

14.2

0

156

67.8

83

75.5

73

60.8

1

48

20.9

19

17.3

29

24.2

2

2

0.9

1

0.9

1

0.8

3

1

0.4

1

0.9

0

0.0

Change in maximum score by category

  Hoffa synovitis

Improvement

16

7.0

6

5.5

10

8.3

0.7380

Stable

196

85.2

98

89.1

98

81.7

Worsening

18

7.8

6

5.5

12

10.0

  Effusion synovitis

Improvement

23

10.0

6

5.5

17

14.2

0.8159

Stable

156

67.8

83

75.5

73

60.8

Worsening

51

22.2

21

19.1

30

25.0