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Table 5 The comparison of outcome measures of Lequesne index and SLS

From: Comparing efficacy of a single intraarticular injection of platelet-rich plasma (PRP) combined with different hyaluronans for knee osteoarthritis: a randomized-controlled clinical trial

 

PRP + Artz

(N = 48)

PRP + HYAJOINT Plus

(N = 47)

A.M.D.

(95% C.I.)

P valueb

Lequesne index Baseline

9.0 ± 3.6

9.1 ± 4.3

− 0.1a (− 1.7, 1.5)

0.897 t

1 month

5.2 ± 3.4

7.4 ± 4.4

−2.1 (−3.5, − 0.8)

0.003*

3 month

5.1 ± 3.7

5.9 ± 3.2

−0.8 (−1.9, 0.3)

0.158

6 month

5.0 ± 3.9

5.8 ± 3.8

−0.8 (−2.1, 0.5)

0.240

P Valuec

(post hoc test)

< 0.001* (B > 1 M; B > 3 M;B > 6 M)

< 0.001*

(B > 1 M; B > 3 M;B > 6 M; 1 M > 3 M;1 M > 6 M)

  

SLS Baseline

31.5 ± 33.8

25.3 ± 21.9

6.2 a (−5.4, 17.8)

0.293t

1 month

35.5 ± 36.8

48.5 ± 44.8

−19.8 (−30.8, − 8.8)

< 0.001*

3 month

39.3 ± 39.4

47.8 ± 35.2

−14.9 (−24.6, − 5.1)

0.003*

6 month

37.4 ± 39.1

44.8 ± 33.9

−13.8 (−23.0, − 4.6)

0.004*

P Valuec

(post hoc test)

0.025*

(n.s.)

< 0.001*

(B < 1 M;B < 3 M;B < 6 M)

  
  1. The values are given as mean ± standard deviation; SLS Single limb stance.; A.M.D. Adjusted mean difference, C.I. confidence interval; B. baseline; n.s. none significant; a M.D. Mean difference; bBetween-group difference using independent samples one-way ANCOVA (baseline data as covariate); cWithin-group difference using repeated measures one-way ANOVA; t independent t-test; *p value < 0.05