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Table 3 Association of Statin use with incidence/progression of MRI features

From: Association between statins and progression of osteoarthritis features on magnetic resonance imaging in a predominantly pre-radiographic cohort: the Vancouver Longitudinal Study of Early Knee Osteoarthritis (VALSEKO): a cohort study

OA incidence/progression definition

Unadjusted OR (95% CI)

Propensity Adjusted OR (95% CI)

Fully adjusted OR (95% CI)

Cartilage score

0.79 (0.21, 3.03)

1.02 (0.23, 4.60)

0.82 (0.17, 4.06)

Osteophyte score

3.09 (0.49, 19.51)

3.87 (0.52, 28.65)

3.48 (0.40, 30.31)

BML score

1.16 (0.30, 4.41)

0.76 (0.17, 3.50)

0.61 (0.12, 3.02)

Effusion progression

1.79 (0.44, 7.26)

3.55 (0.66, 19.19)

2.38 (0.42, 13.63)

  1. OR Odds ratio, BML Bone marrow lesion
  2. Propensity Adjusted OR: adjusted for propensity score only
  3. Fully adjusted OR: adjusted for propensity score, age, sex, BMI
  4. Propensity score model: Statin use ~ hypertension, dyslipidemia, cardiovascular or cerebrovascular disease, diabetes
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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