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Table 2 Diagnostic accuracy results from the included studies

From: Diagnostic accuracy of the Ottawa ankle rule to exclude fractures in acute ankle injuries in adults: a systematic review and meta-analysis

Study TP FP FN TN Sensitivity
(95% CI)
Specificity
(95% CI)
Positive likelihood ratios
(95% CI)
Negative likelihood ratios
(95% CI)
Diagnostic Odds Ratio
(95% CI)
Auley 1998 [1] 48 171 1 137 0.98 (0.89–1.00) 0.44 (0.39–0.50) 1.76 (1.58–1.97) 0.05 (0.01–0.32) 38.46 (5.24–282.17)
Beceren 2013 [3] 235 203 83 445 0.74 (0.69–0.79) 0.69 (0.65–0.72) 2.36 (2.07–2.69) 0.38 (031–0.46) 6.21 (4.60–8.38)
Broomhead 2003 [5] 43 187 0 35 1.00 (0.92–1.00) 0.16 (0.11–0.21) 1.18 (1.10–1.26) 0.07 (0.00–1.14) 16.47 (0.99–273.79)
Can 2008 [6] 33 173 0 45 1.00 (0.89–1.00) 0.21 (0.15–0.27) 1.24 (1.15–1.35) 0.07 (0.00–1.12) 17.57 (1.06–292.27)
Cheng 2016 [7] 68 263 3 45 0.96 (0.88–0.99) 0.15 (0.11–0.19) 1.12 (1.05–1.20) 0.29 (0.09–0.90) 3.88 (1.17–12.86)
Daş 2016 [8] 61 190 1 153 0.98 (0.91–1.00) 0.45 (0.39–0.50) 1.78 (1.61–1.96) 0.04 (0.01–0.25) 49.12 (6.73–358.42)
Glas 2002 [12] 44 119 30 69 0.59 (0.47–0.71) 0.37 (0.0–0.44) 0.94 (0.76–1.17) 1.10 (0.79–1.54) 0.85 (0.49–1.48)
Gomes 2020 [13] 88 278 5 51 0.95 (0.88–0.98) 0.16 (0.12–0.20) 1.12 (1.05–1.20) 0.35 (0.14–0.84) 3.23 (1.25–8.34)
Lucchesi 1995 [16] 9 49 0 21 1.00 (0.66–1.00) 0.30 (0.20–0.42) 1.36 (1.11–1.68) 0.17 (0.01–2.52) 8.25 (0.46–148.27)
Papacostas 2001 [21] 7 15 3 42 0.70 (0.35–0.93) 0.74 (0.60–0.84) 2.66 (1.47–4.82) 0.41 (0.16–1.06) 6.53 (1.49–28.57)
Rosin 1999 [22] 48 190 0 86 1.00 (0.93–1.00) 0.31 (0.26–0.37) 1.44 (1.32–1.57) 0.03 (0.00–0.52) 44.04 (2.68–722.59)
Santelli 2008 [24] 29 66 0 51 1.00 (0.88–1.00) 0.44 (0.34–0.53) 1.74 (1.48–2.06) 0.04 (0.00–0.60) 45.69 (2.73–765.63)
Salt 1997 [23] 74 244 0 247 1.00 (0.95–1.00) 0.50 (0.46–0.55) 2.00 (1.83–2.19) 0.01 (0.00–0.21) 150.83 (9.29–2447.58)
Verma 1997 (prospective) [28] 152 607 2 150 0.99 (0.95–1.00) 0.20 (0.17–0.23) 1.23 (1.18–1.28) 0.07 (0.02–0.26) 18.78 (4.60–76.65)
Verma 1997 (retrospective) [28] 270 2181 0 50 1.00 (0.99–1.00) 0.02 (0.02–0.03) 1.02 (1.01–1.03) 0.08 (0.01–1.32) 12.52 (0.77–203.57)
Wang 2013 [29] 61 65 2 55 0.97 (0.89–1.00) 0.46 (0.37–0.55) 1.79 (1.51–2.12) 0.07 (0.02–0.26) 25.81 (6.03–110.41)
  1. TP True positive, FP False positive, FN False negative, TN True negative, CI Confidence interval