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Table 4 Surgical results and complications between two groups

From: Does local vancomycin powder impregnated with autogenous bone graft and bone substitute decrease the risk of deep surgical site infection in degenerative lumbar spine fusion surgery?—An ambispective study

 

Vancomycin (V)

No Vancomycin (NV)

P value

Numbers of Patients

110

86

 

Blood Loss (mL)

282 ± 280 (150–1100)

297 ± 295 (140–1000)

0.717

Operative Times (mins)

281 ± 72 (200–400)

285 ± 63 (220–410)

0.687

Deep Surgical Site Infection (DSSI)

0 (0%)

3 (3.48%)

0.048*

Surgical-Related Complications (patients)

  

0.350

 Screws breakage or loosening

2

4

 

 Cage Dislodge or migration

0

1

 

 Incidental Durotomy

2

2

 

Vancomycin-Related Complications (patients)

 Red Man syndrome

0

NA

 

 Allergic reaction

0

NA

 

 Renal toxicity

0

NA

 

 Ototoxicity or transient hearing loss

0

NA

 

 Systemic Absorption (Detectable Serum Vancomycin)

0

NA

 

Functional Outcomes

 Visual analogue scale (VAS) over back

1.8 ± 1.3 (1–5)

1.7 ± 1.2 (0–4)

0.581

 Visual analogue scale (VAS) over leg

1.3 ± 0.4 (1–4)

1.2 ± 0.5 (0–3)

0.121

 Oswestry Disability Index (ODI)

31.8 ± 9.6 (16–48)

32.9 ± 10.1 (24–50)

0.438

  1. The percentage was presented in parentheses, NA meant Non-appreciable, f/u meant follow-up
  2. 2 patients had S1 screws loosening in the V group at latest f/u
  3. 2 patients had S1 screws loosening in the NV group at latest f/u. (2: S1 screws, 2: infective non-union)