Vancomycin (V) | No Vancomycin (NV) | P value | |
---|---|---|---|
Numbers of Patients | 110 | 86 | |
Blood Loss (mL) | 282 ± 280 (150–1100) | 297 ± 295 (140–1000) | 0.717 |
Operative Times (mins) | 281 ± 72 (200–400) | 285 ± 63 (220–410) | 0.687 |
Deep Surgical Site Infection (DSSI) | 0 (0%) | 3 (3.48%) | 0.048* |
Surgical-Related Complications (patients) | 0.350 | ||
Screws breakage or loosening | 2 | 4 | |
Cage Dislodge or migration | 0 | 1 | |
Incidental Durotomy | 2 | 2 | |
Vancomycin-Related Complications (patients) | |||
Red Man syndrome | 0 | NA | |
Allergic reaction | 0 | NA | |
Renal toxicity | 0 | NA | |
Ototoxicity or transient hearing loss | 0 | NA | |
Systemic Absorption (Detectable Serum Vancomycin) | 0 | NA | |
Functional Outcomes | |||
Visual analogue scale (VAS) over back | 1.8 ± 1.3 (1–5) | 1.7 ± 1.2 (0–4) | 0.581 |
Visual analogue scale (VAS) over leg | 1.3 ± 0.4 (1–4) | 1.2 ± 0.5 (0–3) | 0.121 |
Oswestry Disability Index (ODI) | 31.8 ± 9.6 (16–48) | 32.9 ± 10.1 (24–50) | 0.438 |