Fig. 3
From: miR-215-5p regulates osteoporosis development and osteogenic differentiation by targeting XIAP
Targeted relationship between miR-215-5p and XIAP. A Potential targets of miR-215-5p were predicted by miRDB, TargetScan and Starbase. B Abnormal expressions of WNK1, RB1, XIAP, CTCF and RUNX1 in OP patients and healthy controls. C Correlation between miR-215-5p and XIAP in OP samples. D Expressions of WNK1, PB1, XIAP, CTCF and RUNX1 after transfection with miR-215-5p mimics in hBMSCs. E Dual-luciferase reporter assay confirmed the targeted relationship between miR-215-5p and XIAP. F qRT-PCR assay was conducted to examine the change of XIAP level before and after β-glycerophosphate treatment in hBMSCs. G Western blot assay was conducted to examine the change of XIAP level before and after β-glycerophosphate treatment in hBMSCs. H Effect of miR-215-5p transfection on XIAP level was determined by qRT-PCR analysis. I Effect of miR-215-5p transfection on XIAP level was determined by western blot analysis