Fig. 2

Schematic representation and conservation of CHST3. A Graphical representation of CHST3, the orange area indicate sulfotransferase domain. Amino acids are numbered with integers. The identified variants are indicated by lines. B Clustal Omega multiple sequence alignment of CHST3 from diverse vertebrate species showing conservation of Leucine 197 and Arginine 221in all orthologues. The conserved amino acids are highlighted in yellow. The asterisk (*) signs below the alignment represent evolutionary conserved amino acids, a colon indicates highly conserved amino acids, and the periods symbolize less conserved amino acid changes