Genetic variants of interleukin 1B and 6 are associated with clinical outcome of surgically treated lumbar degenerative disc disease

Table 4 IL1B haplotype association (GLM and hapscore) with the change in pain after surgery

Change in max pain GLM model
Haploblock	Haplotype	Haplotype frequency	diff (95% CI)	hap score^a	p
IL1B rs1143634-rs1143633	C-A T-G C-G	0.34 0.25 0.38	-0.7 (-1.2 – (-)0.3) -0.2 (-0.7 – 0.3) -3.8 (reference)	-2.46742 1.59408 0.38051	*0.001* 0.37 -

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