Fig. 3

The assessed PPARγ protein expression in primary bone tumors. The PPARγ protein expression level was evaluated in different bone tumor tissue and non-cancerous paired margins. The enhanced level of PPARγ was detected in bone tissues compared to healthy tissues (a), and malignant tumors compared to benign tumors (b). The osteosarcoma and Ewing Sarcoma tumors showed higher PPARγ expression level compared to GCT tumors; while GCT tumors showed over expression of PPARγ compared to healthy bone tissues (c). The higher PPARγ expression was detected in osteosarcoma and Ewing Sarcoma tumors compared to healthy bone tissues, also osteosarcoma tumors showed the highest expression compared to other tumors (c). The statistical differences between groups are shown as asterisk (**= P < 0.01, ****= P < 0.0001)