Table 2 Comparison of various parameters of T2DM patients with differently BMD T value
Normal (n = 193) | Osteopenia (n = 140) | Osteoporosis (n = 85) | |
|---|---|---|---|
Age, years | 58.4 ± 6.6 | 61.8 ± 7.0* | 64.5 ± 7.2*# |
Diabetic duration, years | 8.2 ± 6.9 | 9.6 ± 7.1* | 10.7 ± 9.2* |
Systolic blood pressure, mmHg | 140.7 ± 25.0 | 145.5 ± 25.2 | 142.8 ± 25.0 |
Diastolic blood pressure, mmHg | 84.1 ± 8.6 | 88.6 ± 71.3 | 82.3 ± 6.9 |
BMI, Kg/m2 | 25.2 ± 3.2 | 24.0 ± 3.0* | 23.5 ± 3.3* |
Laboratory findings | |||
FBG, mmol/L | 6.4 ± 1.7 | 6.7 ± 2.0* | 6.7 ± 2.1* |
HbA1c, mmol/L | 9.1 ± 2.1 | 9.1 ± 1.9 | 9.1 ± 2.1 |
TC, mmol/L | 4.5 ± 1.3 | 4.5 ± 1.2 | 4.7 ± 1.3 |
TG, mmol/L | 2.0 ± 1.8 | 2.0 ± 1.3 | 1.6 ± 0.9*# |
HDL-c, mmol/L | 1.0 ± 1.3 | 1.1 ± 0.3 | 1.1 ± 0.3*# |
LDL-c, mmol/L | 2.7 ± 1.0 | 2.7 ± 1.0 | 3.0 ± 1.1 |
Albumin, g/L | 40.5 ± 3.3 | 40.3 ± 3.5 | 38.6 ± 3.2*# |
Creatinine, µmol/L | 65.9 ± 34.1 | 62.9 ± 27.0* | 55.0 ± 29.8*# |
Cystatin C, mg/L | 0.96 ± 0.34 | 1.02 ± 0.32* | 1.04 ± 0.33* |
CCR, | 8.3 ± 1.6 | 7.4 ± 1.3* | 6.3 ± 1.3*# |
Uric, µmmol/L | 346.3 ± 91.7 | 325.1 ± 93* | 297.9 ± 86.5*# |
PTH, pg/ml | 36.9 ± 14.7 | 38.9 ± 15.6 | 39.1 ± 16.7 |
PINP, ng/ml | 37.4 ± 17.7 | 41.9 ± 17.6* | 46.7 ± 24.4* |
β-CTX, ng/ml | 0.41 ± 0.20 | 0.47 ± 0.25* | 0.53 ± 0.29* |
25(OH)D, ng/ml | 22.9 ± 7.6 | 22.9 ± 8.9 | 21.0 ± 7.3* |
Calcium, mmol/L | 2.25 ± 0.11 | 2.24 ± 0.10 | 2.24 ± 0.11* |
ASM/height2, Kg/m2 | 7.1 ± 1.3 | 6.4 ± 0.9* | 6.2 ± 1.3*# |
BMD | |||
Total lumbar, g/cm2 | 1.257 ± 0.157 | 1.051 ± 0.147* | 0.932 ± 0.176*# |
Femur neck, g/cm2 | 1.003 ± 0.110 | 0.826 ± 0.092* | 0.766 ± 0.128*# |
Total hip, g/cm2 | 1.070 ± 0.112 | 0.899 ± 0.106* | 0.839 ± 0.130*# |