Evaluation of the safety of tranexamic acid use in pediatric patients undergoing spinal fusion surgery: a retrospective comparative cohort study

Table 2 Frequency of new onset complications in the pediatric fusion population, stratified by TXA Use.^a

	TXA (n = 402)	No TXA (n = 2,231)	Odds Ratio	P value
New onset seizures	0	< 11^b	0 (0, 3.72) ^c	> 0.99 ^c
Pulmonary embolism	0	< 11^b	0 (0, 5.57)	> 0.99
Deep Vein Thrombosis	< 11 ^b	< 11 ^b	1.39 (0.11, 8.35)	0.56
Stroke	0	0	-	-
Total	< 11 ^b	12 (0.31%, 0.94%)	0.46 (0.04, 2.90)	0.71

^a 95% confidence intervals shown in parenthesis where applicable. The Fisher exact test was used to calculate p-values
^b To protect patient privacy, data in cells with fewer than 11 instances is supressed
^c 15 patients with a prior history of seizure were excluded

ISSN: 1471-2474