Fig. 8

Morphological evaluation of each group by gross observation at 4 weeks, 8 weeks, and 12 weeks postoperatively. In the control group, typical osteomyelitis and severe tibia damage could be seen (a), and in the BMSC sheets group, the defects were partially healed with uncontrolled infection (b). It could be observed that defects were gradually cured with the absorption of bone substitutes, fibrous tissue was formed, and infection was effectively controlled in Groups C and D (c, d)