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Table 1 The advantage and disadvantage of each assessment for bone healing

From: The progress in quantitative evaluation of callus during distraction osteogenesis

Method

Advantage

Disadvantage

Radiography

Simple, fast and convenient;

The most common assessment for bone union

Limited sensitivity for early callus formation

DXA

Golden standard for BMD;

Indirect assessment for bony microstructural

Expensive;

Limited for clinical application;

Limited for limb assessment

Ultrasound

Cheap, portable, ionizing radiation free

and early monitoring

Relatively limited sensitivity;

Limited access to the force line of limb;

Unaccessible for later osteotomy end space

QCT

High accuracy and small error;

Directly related to histological specimens

Expensive;

High radiation dose;

Limited for clinical application

Biomechanical evaluation

Directly assessed the bone quality

Usually utilized in lab work

Biochemical markers

Theoretical basis for delayed bone union

Limited for clinical application