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Table 4 Scenario analyses, CRFA versus HA

From: Cooled radiofrequency ablation of the genicular nerves for chronic pain due to osteoarthritis of the knee: a cost-effectiveness analysis compared with intra-articular hyaluronan injections based on trial data

Analysis

Incremental QALY gain

Incremental cost

ICER

Scenario 1: 12-month time horizon, EQ-5D levels in HA group persist from 6 months

0.056

US$1707

US$30,275

Scenario 2: 12-month time horizon, HA patients receive a second injection and get the same change in EQ-5D for the second 6 months

0.043

US$832

US$19,316

Scenario 3: 6-month time horizon, single office-based GNB and HA injection (assumes CRFA is administered in non-office outpatient facility setting)

0.020

US$1422

US$71,314

Scenario 4: 12-month time horizon, HA patients cross over to CRFA at 6 months

0.025

-US$875

CRFA is dominant

  1. Abbreviations: CRFA Cooled radiofrequency ablation, GNB Genicular nerve block, HA Hyaluronan, ICER Incremental cost-effectiveness ratio, QALY Quality-adjusted life-year