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Table 7 The value of each marker in diagnosing osteoporosis

From: Association of bone-related biomarkers with femoral neck bone strength

Parameters AUC 95% CI S.E Cut-off Sensitivity (%) Specificity (%) P-value
OC 0.767 0.672 ~ 0.862 0.048 16.98 0.611 0.926  < 0.0001
PINP 0.726 0.628 ~ 0.824 0.050 61.26 0.593 0.889  < 0.0001
CTX 0.842 0.769 ~ 0.914 0.037 0.59 0.685 0.852  < 0.0001
COL-I 0.916 0.861 ~ 0.972 0.028 0.46 0.852 0.907  < 0.0001
OPN 0.891 0.819 ~ 0.962 0.036 0.44 0.870 0.907  < 0.0001
  1. AUC the area under the curve, CTX C-terminal telopeptide of type I collagen, PINP type I procollagen N-terminal propeptide, OC osteocalcin, OPN osteopontin, COL- I type I collagen