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Table 6 The value of each marker in diagnosing femoral neck osteopenia

From: Association of bone-related biomarkers with femoral neck bone strength

Parameters

AUC

95% CI

S.E

Cut-off

Sensitivity (%)

Specificity (%)

P-value

OC

0.741

0.648 ~ 0.834

0.047

15.74

0.481

0.963

 < 0.0001

PINP

0.695

0.595 ~ 0.794

0.051

58.99

0.494

0.926

0.003

CTX

0.914

0.852 ~ 0.976

0.032

0.41

0.864

0.889

 < 0.0001

COL-I

0.802

0.701 ~ 0.904

0.052

0.63

0.975

0.963

 < 0.0001

OPN

0.908

0.851 ~ 0.965

0.029

0.14

0.901

0.852

 < 0.0001

  1. AUC the area under the curve, CTX C-terminal telopeptide of type I collagen, PINP type I procollagen N-terminal propeptide, OC osteocalcin, OPN osteopontin, COL- I type I collagen