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Table 1 Comparison of general clinical information of the patients in each group

From: Association of bone-related biomarkers with femoral neck bone strength

Parameters Normal a
(n = 27, fragility fracture n = 0)
Osteopenia b (n = 27, fragility fracture n = 0) Osteoporosis c (n = 27, fragility fracture n = 15) Severe osteoporosis d (n = 27, fragility fracture n = 27) P-value
Gender
(male/female)
6/21 7/20 6/21 5/22 0.934
Age (years) 51.48 ± 10.71 60.30 ± 6.03* 63.00 ± 9.05* 69.30 ± 8.97*#  < 0.0001
BMI (kg/cm2) 24.85 ± 3.57 24.76 ± 3.89 24.88 ± 2.78 23.72 ± 3.37 0.545
Femoral neck BMD (g/cm2) 0.94 ± 0.12 0.80 ± 0.10* 0.77 ± 0.09* 0.61 ± 0.10*#▲  < 0.0001
Femoral neck
T-score
0.00 ± 0.90 -1.50 ± 0.48* -1.75 ± 0.75* -2.91 ± 0.40*#▲  < 0.0001
Femoral neck Lmax (KN) 3.00 ± 0.52 1.67 ± 0.46* 1.12 ± 0.26* 0.59 ± 0.19*#▲  < 0.0001
  1. Data are presented as the mean ± SD for age, BMI, femoral neck BMD, femoral neck T-score and femoral neck Lmax
  2. a T-score ≥ -1.0
  3. b T-score < -1.0 and > -2.5
  4. c At least one of the following criteria fulfilled: (a) T-score ≤ -2.5; (b) femoral neck fragile fracture)
  5. d Fragility fracture with a T-score ≤ -2.5
  6. *P < 0.05, compared with normal group
  7. #P < 0.05, compared with osteopenia group
  8. P < 0.05, compared with osteoporosis group
  9. BMI body mass index, BMD bone mineral density