Impact of heterotopic ossification following lumbar total disk replacement: a systematic review

Table 4 Outcome measures

Ref	HO at the surgical level	Patients with indications of HO at index level	Percentage of patients with HO	HO graded by McAfee or other scale?	Mean percentage change in visual analogue scores for perceived patient pain	Mean percentage change in Oswestry disability scores of patients	Mean percentage change in range of motion at the index level of the artificial disc(s)
[52]	N/A	41	91.1	YES	61.1	60.1	N/A
[47]	11	11	5.88	NO	73.6	66.4	31.8
[67]	30	N/A	50	YES	N/A	N/A	N/A
[68]	26	N/A	74.3	YES	81.6	89.9	N/A
[53]	37	37	23.7	YES	82.6	68.9	10.6
[54]	3	3	5.36	NO	68.5	64.7	N/A
[56]	25	N/A	71.4	YES	82.8	68.1	-37
[55]	N/A	1	3.33	NO	82.6	62.8	27.99
[57]	0	0	0	YES	N/A	81.5	N/A
[58]	12	N/A	85.7	NO	N/A	N/A	N/A
[59]	N/A	7	20	NO	74.4	69.3	N/A
[69]	19	N/A	83	YES	N/A	N/A	N/A
[60]	25	N/A	30.5	YES	N/A	N/A	N/A
[61]	N/A	7	15.2	NO	N/A	N/A	N/A
[70]	N/A	39	73.6	YES	N/A	N/A	N/A
[48]	N/A	32,36	15.9,19.3	NO	69.6, 71.8	63.7, 66.1	15.3
[62]	N/A	3	3	NO	N/A	N/A	N/A
[49]	17	17	18.9	NO	55.7	49.4	N/A
[50]	3,1	3,1	1.6, 1.1	NO	74,68	67, 61	N/A
[63]	0	0	0	yes	50	50	N/A
[64]	3	3	4.69	YES	57.9	47.3	N/A
[71]	N/A	4	14.2	NO	N/A	N/A	N/A
[66]	0	0	0	YES	64.9	69.3	N/A
[72]	7	7	6.6	NO	N/A	N/A	N/A
[51]	1	1	2.22	YES	N/A	N/A	N/A
[65]	N/A	1	3.56	NO	N/A	30.2	N/A

HO Heterotopic ossification, VAS Visual Analogue Scores for Perceived Pain, ODI Oswestry Disability Index, ROM Range Of Motion at index level

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