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Table 2 Results and comparison of micro-CT microstructure indexes of vertebral bodies between the two groups

From: Early effects of ovariectomy on bone microstructure, bone turnover markers and mechanical properties in rats

 

Time

OVX Group (n = 4)

Control Group (n = 4)

P

BV/TV (%)

1 week

0.41 ± 0.03

0.42 ± 0.08

0.628

4 weeks

0.34 ± 0.04

0.46 ± 0.03

0.001

8 weeks

0.34 ± 0.03

0.44 ± 0.05

0.005

12 weeks

0.30 ± 0.03

0.45 ± 0.03

<0.001

16 weeks

0.30 ± 0.02

0.47 ± 0.04

<0.001

P

0.003

0.832

 

Conn.D (1/mm3)

1 week

110.90 ± 18.05

115.99 ± 16.36

0.625

4 weeks

90.63 ± 12.66

90.87 ± 22.21

0.982

8 weeks

96.99 ± 9.13

84.43 ± 13.40

0.232

12 weeks

73.71 ± 5.41

100.08 ± 15.51

0.016

16 weeks

67.52 ± 8.99

97.93 ± 16.27

0.006

P

0.001

0.155

 

Tb.N (1/mm)

1 week

4.55 ± 0.38

4.69 ± 0.36

0.586

4 weeks

4.23 ± 0.18

4.64 ± 0.61

0.117

8 weeks

4.39 ± 0.27

4.78 ± 0.46

0.138

12 weeks

3.88 ± 0.42

5.02 ± 0.19

<0.001

16 weeks

3.69 ± 0.20

5.09 ± 0.29

<0.001

P

0.008

0.470

 

Tb.Th (mm)

1 week

0.08 ± 0.00

0.08 ± 0.01

0.452

4 weeks

0.08 ± 0.00

0.09 ± 0.00

0.006

8 weeks

0.07 ± 0.00

0.08 ± 0.00

0.019

12 weeks

0.07 ± 0.00

0.08 ± 0.00

0.032

16 weeks

0.07 ± 0.00

0.08 ± 0.00

0.017

P

0.281

0.687

 

Tb.Sp (mm)

1 week

0.20 ± 0.02

0.19 ± 0.02

0.826

4 weeks

0.21 ± 0.01

0.19 ± 0.03

0.204

8 weeks

0.20 ± 0.01

0.18 ± 0.01

0.251

12 weeks

0.23 ± 0.03

0.17 ± 0.00

<0.001

16 weeks

0.25 ± 0.01

0.17 ± 0.01

<0.001

P

0.018

0.339