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Table 4 Comparison of different biomarkers between PJI and aseptic failures

From: Serum D-lactate, a novel serological biomarker, is promising for the diagnosis of periprosthetic joint infection

Biomarkers

PJI(n=26)

Aseptic(n=26)

Statistic tests

P

TT(s)b

19.42 ± 2.04

19.85 ± 1.30

t= - 0.892

0.377

PT(s)a

11.90(11.38 - 12.93)

11.40(11.25 - 11.83)

Z= - 2.310

0.021*

INRa

1.04(0.98 - 1.11)

0.99(0.97 - 1.03)

Z= - 2.283

0.022*

APTT (s)a

32.95(31.30 - 35.83)

30.95(29.68 - 32.70)

Z= - 2.608

0.009*

FDP (ug/ml)a

3.66(2.38 - 6.55)

1.92(1.14 - 3.75)

Z= - 2.270

0.023*

D-dimer (ng/ml)a

530.00(257.50 - 886.50)

248.00(110.50 - 610.50)

Z= - 2.115

0.034*

FIB (g/L)a

4.10(3.48 - 4.48)

3.01(2.54 - 3.57)

Z= - 3.615

0.000*

ESR (mm/h)

50.00(30.00 – 68.00)

20.00(14.00 – 32.00)

Z= - 3.718

0.000*

Serum D-lactate (mmol/L)a

1.70(1.45 - 2.33)

0.44(0.60 - 1.33)

Z= - 3.651

0.000*

Synovial D-lactate (mmol/L)b

2.43 ± 0.58

1.29 ± 0.83

t= 5.530

0.000*

SF WBC count (cells/μl)a

12174.00(5622.00 – 26347.00)

2365.00(1339.00 – 9706.50)

Z= - 3.318

0.001*

SF PMN%a

95.00(90.00 – 96.50)

51.65(40.00 – 79.25)

Z= - 4.315

0.000*

  1. PJI Periprosthetic joint infection, TT Thrombin time, PT Prothrombin time, INR International normalized ratio, APTT Activated partial thromboplastin time, FDP Fibrinogen degradation products, FIB Fibrinogen, ESR Erythrocyte sedimentation rate, SF synovial fluid, WBC White blood cell, PMN% Polymorphonuclear neutrophil percentage
  2. aThe data was shown as median (interquartile range)
  3. bThe data was expressed as mean ±SD. SD, standard deviation
  4. * P<0.05