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Table 4 Association of biomarker levels with age, BMI, KL grade, and knee pain

From: Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a pilot study

Variable

Biomarker

sCOMP

sHA

sPIICP

r

p-value

r

p-value

r

p-value

Age

0.2574

0.0002

0.2523

0.0002

−0.5807

< 0.0001

BMI

0.2150

0.0016

−0.0921

0.1818

−0.2225

0.0011

KL grade

0.2417

0.0004

0.1399

0.0419

−0.6776

< 0.0001

Resting VAS

0.1607

0.0192

0.0263

0.7029

−0.4442

< 0.0001

Walking VAS

0.0624

0.3657

0.0059

0.9314

−0.4184

< 0.0001

  1. Correlation analysis between biomarker levels and the variables was performed using Spearman’s rank correlation coefficient (r). All reported p-values are two-tailed. p-values < 0.05 were considered statistically significant and indicated in bold