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Table 3 Correlation between biomarker levels in the total population, healthy individuals, and patients with EOA or LOA

From: Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a pilot study

Biomarkers

Total population

Healthy

EOA

LOA

r

p

r

p

r

p

r

p

COMP vs HA

0.121

> 0.05

0.072

> 0.05

0.017

> 0.05

0.177

< 0.05

COMP vs PIICP

−0.184

< 0.01

0.086

> 0.05

0.448

< 0.01

−0.307

< 0.0001

PIICP vs HA

−0.030

> 0.05

0.050

> 0.05

−0.117

> 0.05

0.123

> 0.05

  1. EOA Early Osteoarthritis, LOA Late Osteoarthritis. Correlation analysis between biomarker levels was performed using Spearman’s rank correlation coefficient (r). All reported p-values are two-tailed. p-values < 0.05 were considered statistically significant and indicated in bold