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Table 4 Participants, demographics and clinical characteristics across included studies

From: Head kinematics in patients with neck pain compared to asymptomatic controls: a systematic review

Publication

Sample

Age (years)

Mean (SD)

Pain intensity

(0–100 scale) Mean (SD)

Symptom duration

a priori defined

Authors’ definition of cases

Authors’ definition of controls regarding neck impairments

Baydal-Bertomeu et al.  [57]

WAD 30 (15 F)

C 29 (15 F)

20-50a

20-50a

NA

NA

>  6 months and < 1 year

WAD gradeb II and III with altered mobility of the neck

No WAD

Descarreaux et al. [58]

INP 19 (16 F)

C 20 (13 F)

38.7 (10.7)

32.5 (8.8)

23 (20)

NA

At least one episode of neck pain in the last 6 months

Suffering from non-traumatic chronic neck pain on a persistent or recurrent basis

Without any prior or current experience of spinal pain, cervicobrachial pain or other diffuse pain conditions

De Zoete et al. [59]

INP 50 (30 F)

C 50 (27 F

35.5 (24.0–55.3)a

34.5 (26.0–58.0)a

30 (18.77)

NA

12 weeks or longer

Neck pain of at least 4/10 NRS (inquired date)

No current neck pain, had never sought treatment for neck pain

Ernst et al. [60]

INP 25 (14 F)

WAD 13 (7 F)

C 38 (21 F)

31.7 (12.03)

41.1 (11.4)

35.1 (13.1)

20.1 (21.5)

36.1 (17.8)

0 (0)

>  3 months

Traumatic or non-traumatic NP and a minimum Neck Disability Index score of 10%

No history of NP for which they sought treatment and a Neck Disability Index Score of less than 4%

Gadotti et al. [61]

WAD 5 (2 F)

C 15 (10 F)

25.6 (4.9)

24.8 (1.9)

40 (20–60 a 3-6e)

NA

NA

WAD gradeb I-III

No previous history of persistent neck pain, injury or visual problems

Grip et al. [62]

INP 21 (14 F)

WAD 25 (17 F)

C 24 (16 F)

49 (16)

49 (15)

50 (18)

49.2 (20.8)

66.1 (18.8)

0.5 (2.1)

Persistent symptoms

WAD: gradeb I and II

INP: muscular symptoms without paraesthesia

Occasional neck or back pain accepted as long as free from symptoms in the past 3 months.

Hage et al. [63]

INP 9 (4 F)

C 15 (3 F)

31 (14)

24 (3)

30 (0)

0 (0)

NA

3/10 NRS or grater and NDI > 8%

Absence of neck pain episodes in the last 6 months and NDI < = 8%

Kristjansson et al. [64]

WAD 20 (20 F)

C 20 (20 F)

30.8 (9.1)

29.3 (8.6)

46.8 (21.8)

NA

>  6 months and <  6 years

WAD gradeb I and II

No musculoskeletal pain or injury in the neck or upper limbs

Kristjansson and Oddsdottir [65]

INP 18 (11 F)

WAD 18 (16 F)

C 18 (8 F)

38.0 (8.3)

35.5 (11.9)

32.3 (10.9)

32 (15) /80 (14)d

19 (14)/ 67 (26)d-

>  6 months and < 2 years

WAD: gradeb II after motor vehicle collision with no prior symptoms in the head or neck and pain score >  30 during last week

INP: pain score >  30 during last week

No history of musculoskeletal pain or injury in the neck

Lemmers et al. [66]

INP 35 (19 F)

C 100 (50 F)

48 (15)

44 (16)

40 (20)

NA

NA

Cervical pain of unknown origin

Presence of non-specific

neck pain at the time of invitation

Meisingset et al. [67]

INP 75 (55 F)

C 91 (48 F)

43.1 (12.9)

40.8 (13.8)

46 (14)

NA

Current neck pain episode lasting > 2 weeks

Non- traumatic neck pain as the main problem with a pain score of ≥30 at day of testing

No episode of neck pain within the last 3 months and no neck trauma

Oddsdottir

et al. [68]

WAD 34 (28 F)

C 31 (16 F)

42.1 (8.7)

37.9 (16.7)

30/78d

NA

>  6 months

WAD gradeb II with history of symptoms from the head or neck after 1 or more MVCs and pain intensity scoring > 40

No history of musculoskeletal pain or injury in the neck

Ohberg et al. [69]

WAD 59 (30 F)

C 56 (27 F)

38.1 (10.6)

37.3 (10.9)

NA

NA

>  3 months

Chronic WAD of different gradesb

Without chronic head, neck or back pain

Occasional neck or back pain accepted as long as free from symptoms during investigation.

Osterbauer

et al. [70]

WAD 30 (25 F)

C 51 (36 F)

27 (5)

24 (4)

47 (27)

9 (11) daysc

Symptomatic whiplash-type neck trauma as a result of a rear end impact

No history of symptomatic neck trauma for which they sought treatment in the past year

Neck disability index score less than 5%

Röijezon et al. [71]

INP 102 (102 F)

C 33 (33 F)

INP 51 (9)

C 47 (10)

54 (1.6)

NA

>  3 months

Women with neck pain of non-traumatic origin with a decreased physical functioning measured as > 9 normalized points of the first 19 items in the Disability Arm Shoulder Hand questionnaire

Healthy women

Rutledge et al. [72]

INP 19 (5 F)

C 22 (4 F)

27.5 (13.1)

19.9 (1.9)

46 (17)

0 (0)

–

Neck pain score above 30

Neck pain score 0 and symmetric

lateral flexion regarding range and tissue resistance

Sarig Bahat et al. [73]

NP 25 (16 F):

- INP 18 (NA)

- WAD 7 (NA)

C 42 (31 F)

39 (12.7)

NA

NA

35.3 (12.4)

33 (20)

NA

NA

NA

>  6 weeks

Neck pain, either insidious or after whiplash injury, with or without referral to the upper limb

No history of spinal pain during the past year

Sarig Bahat et al. [74]

NP 33 (20 F):

- INP 21 (NA)

- WAD 12 (NA)

C 22 (8 F)

37.5 (9.9)

33 (6.78)

36.4 (17.2)

NA

>  3 months

Chronic neck pain with or without referral to the upper limb and neck range of motion more than 40° in each direction

No physical complaints in the neck region

Sarig Bahat et al. [75]

INP 12 (9 F)f

WAD: 8 (5 F)f

C 20 (10 F)

40.3 (9.8)

45.8 (16.5)

30.3 (6.2)f

NA

>  3 months

Absence of upper limb referral, and NDI > 10%

No history of neck pain in the last 3 months and NDI < 4%

Sjölander et al. [76]

INP 9 (9 F)

WAD 7 (5 F)

C 16 (13 F)

40 (9)

45 (11)

41 (9)

52 (16)

45 (19)

NA

>  6 months

Neck pain

Absence of current, previous (over the last year) or repeated periods of neck pain

Takasaki et al. [77]

WAD14 (9 F)

C 14 (8 F)

33.4 (10.8)

35.4 (10.7)

29 (16)

NA

>  3 months and

<  6 years

WAD subjects after a car accident with a score of greater than 8% on the Neck Disability Index

No history of a whiplash injury and no current neck pain or headache

Tsang et al. [78]

INP 34 (25 F)

C 34 (25 F)

38.4 (10.8)

34.3 (9.0)

38.9 (15.8)

NA

>  3 months or mostly presented over the last 12 months

Severity of neck condition had required medical care

No history of neck pain that required medical care over the last 12 months.

Tsang et al. [79]

INP 30 (22 F)

C 30 (21 F)

38.3 (11.3)

35.1 (9.0)

37.6 (12.2)

NA

>  3 months or mostly presented over the last 12 months

Severity of neck condition had required medical care

No history of neck pain that required medical care over the last 12 months

Vikne et al. [80]

WAD 15 (9 F)

C 15 (9 F)

40.1 (8.7)

38.7 (8.8)

31 (14)

NA

>  6 months

WAD gradeb II which started less than 72 h after the motor vehicle accident

No WAD

Woodhouse et al. [81]

INP 45 (32 F)

WAD 35 (23 F)

C 48 (24 F)

43 (32–53)e

40 (32–48)e

38 (27–48)e

40 (30–50)e

60 (40–70)e

0 (0–0)e

>  6 months and

<  10 years

WAD: gradeb I and II suffering from NP and/or headache after a car collision with onset of symptoms within 48 h

INP: no history of neck trauma

No previous or current neck pain or history of neck trauma

Yang et al. [82]

NP 18 (7 F)

C 18 (8 F)

25.3 (4.6)

23.8 (3.9)

NA

NA

NA-

Mechanical neck disorder diagnosed by a physician and who had sought medical treatment within the past 6 weeks

No history of cervical trauma, surgery or pain

Zhou et al. [83]

NP 28 (16 F)

C 23 (14 F)

45 (25–69) a

23 (23–30) a

60 (20)

NA

>  3 months

Mechanical or myofascial neck pain with at least one active trigger point in the cervico-thoracic or shoulder girdle region

Healthy university-aged participants

  1. a range, b WAD severity grade classification according to the Quebec Task Force Scale, c measured mean (SD), d minimal pain/ maximal pain mean (SD), e median value (interquartile range) f data obtained by authors
  2. C controls, F female, INP idiopathic neck pain, NA no data available, NP unclassified neck pain (without description of onset mode), NDI neck disability index, WAD whiplash associated disorder