Fig. 6

RvD1 regulates the OA-FLS cell cycle by regulating YAP expression. A Cyclin D1, cyclin B1, PCNA, and p53 were measured by western blot analysis in OA-FLSs after incubation with 200 nM RvD1 or 1 μM verteporfin or both RvD1 and Verteporfin for 48 h. B YAP was measured by western blot analysis in non-OA FLSs after incubation with 200 nM RvD1 or 1 μM verteporfin for 48 h. ns: not significant; *P < 0.05; **P < 0.01 compared with the OA-FLS group. All experiments were repeated three times independently