Fig. 1

FLS extraction and identification and synovial tissue detection. A Optical microscopy showed third generations of FLS fusiform (100× magnification). B Immunofluorescence staining of vimentin in FLSs (200 × magnification). C YAP and cyclin D1 expression was measured by western blot analysis in normal and OA synovium. *P < 0.05 as comparison with OA-FLS group. All experiments were repeated three times independently