Authors | Year | N° of patients | Mean age, yrs | Fixation | Bone graft | Union rate and mean time to union, mths | Outcome | Mean follow-up, mths |
---|---|---|---|---|---|---|---|---|
Intertrochanteric femoral non-unions | ||||||||
Haidukewych [29] | 2003 | 20 | 58 | Blade plate(11), DHS (5), DCS (3), Cephalomedullary nail (1) | Autograft (17), allograft (3) | 95% (19/20) TTU = n/a | 16/19 w/o pain 0 AVN | 27 |
Said [30] | 2006 | 26 | 61 | DHS (8), DHS + VSTO (6), blade plate + VSTO (4), THA (3), endoprosthesis (5) | None | 100% (18/18) TTU = 4 | 16/18 w/o pain, 2/18 occasional pain 1 AVN | 31 |
Xue [31] | 2017 | 23 | 60 | DHS(3), Cephalomedullary nail (9) proximal locking plate (3) THA (4) antibiotic rod staged to proximal locking plate (4) | Iliac crest autograft (6) None (13) | 100% (19/19) TTU = 4,7 | HHS: 28,9 (pre-op) to 83,8 (post-op) | 16 |
Lawrenz [32] | 2019 | 2 | 64 | 95° blade plate (2) | None (2) | 100% (2/2) TTU = n/a | First revision 95° blade plate (1) 130° blade plate (1) Second revision 130° blade plate (1) 2/2 no pain at 12 months post-op FU | 36 |
Subtrochanteric femoral non-unions | ||||||||
Haidukewych [33] | 2004 | 21 | 55 | Cephalomedullary nail (8) Standard anterograde IMN (7) 95° blade plate (5) DHS (1) 95° DCS (1) dual large-fragment plates (1) | Autograft (8) Allograft (6) Both (3) Free vascularized fibula (1) | 95% (20/21) TTU = n/a | 16/20 with no pain 4/20 mild pain | 12 |
Barquet [34] | 2004 | 26 | 63 | Long gamma cephalomedullary nail | Autograft (5) None (21) | 96% (25/26) TTU = 7 | 21/26 restored to preinjury functional status | 27 |
De vries [17] | 2006 | 33 | 57 | 95° blade plate (24) 100–125° blade plate (7) 90°blade plate (2) | Iliac crest autograft (13) Local bone graft (1) DBX (10) | 97% (32/33) TTU = 5 | 25/33 good or excellent Merle d’Aubigne score 5 complications requiring reoperation | 31 |
Park [35] | 2011 | 16 | 58 | Blade plate (16) | Iliac crest autograft (1/14) | 94% (15/16) TTU = 7 | Revision: THA for AVN and mechanical failure (1) 1/14 great trochanter bursitis 12/14 no pain HHS: 88 (12 months post-op) Sanders functional rating scale: 14/16 (88%) good or excellent | 24 |
Giannoudis [13] | 2013 | 14 | 65 | 95° blade plate (11) IMN (3) | RIA graft (14) Osteoinductive factor (Osigraft Olympus) (14) MSCs from the iliac crest (14) | 93% (13/14) TTU = 7 | 8/14 no complications 2/14 died during follow up 1/14 revision to double plate construct 1/14 pulmonary embolism 1/14 below knee deep vein thrombosis 16 failures, of which 11 were from the infected group | 26 |
Amorosa [36] | 2014 | 71 (57 non-infected non-unions, 21 infected non-unions) | 60 | 95° blade plate (71) | n/a | 91,2% in the not infected group TTU = 6 | 24 | |
Rollo [27] | 2016 | 35 | 72,4 | blade plate (35) | Femoral medial strut allograft (22) None (13) | 100% (22/22) in the strut allograft group TTU = 8 69% (9/13) in no allograft group TTU = 10 | HHS for allograft group: 18.3 (pre-op) 85.3 (post-op) HHS for no allograft group 17.9 (pre-op) 83.2 (post-op) | 12 |
De Biase [37] | 2018 | 2 | 72 | Blade plate (2) | None (2) | 100% (2/2) TTU = 6 | n/a | 36 |