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Table 3 Pressure pain sensitization outcomes at T2 and T3a

From: Duloxetine in OsteoArthritis (DOA) study: effects of duloxetine on pain and function in end-stage hip and knee OA – a pragmatic enriched randomized controlled trial

 

T0

T2

p-value (T0-T2)

T3

p-value (T0-T3)

Total group

 Joint

3.9 (3.4, 4.5)

4.2 (3.6, 4.8)

0.620

3.9 (3.3, 4.6)

0.849

 Remote

3.4 (2.8, 3.9)

3.6 (3.0, 4.3)

0.554

3.86 (3.2, 4.5)

0.249

Knee

 Joint

3.9 (3.0, 4.7)

3.9 (3.1, 4.8)

0.896

3.8 (2.9, 4.7)

0.964

 Remote

3.3 (2.4, 4.1)

3.7 (2.8, 4.7)

0.478

4.1 (3.1, 5.1)

0.220

Hip

 Joint

4.1 (3.2, 4.9)

4.5 (3.5, 5.5)

0.480

4.0 (3.0, 5.0)

0.972

 Remote

3.5 (2.8, 4.2)

3.5 (2.6, 4.3)

0.999

3.6 (2.8, 4.4)

0.806

  1. aAdjusted mean value of peak force in kg (95% CI); Missing data range: 8.7–9.6%; Post hoc Bonferroni correction was performed, results were not significantly different