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Table 2 RF, ACPA, and anti-CarP Ab in patients with RA

From: Serum rheumatoid factor IgA, anti-citrullinated peptide antibodies with secretory components, and anti-carbamylated protein antibodies associate with interstitial lung disease in rheumatoid arthritis

 

ILD

 

UIP

 

NSIP

 

AD

emphysema

 

CLD(+)

 

CLD(−)

 

P

 

P

 

P

 

P

 

P

 

P

 

RF, U/ml (SD)

510.9 (1213.6)

0.0025

501.2 (992.0)

0.0071

517.5 (1348.2)

0.0320

233.6 (362.6)

0.0149

871.4 (1993.6)

0.0002

443.8 (1133.3)

9.58X10−5

235.6 (569.9)

RF IgA, U/ml (SD)

206.6 (400.5)

1.13X10−8

263.5 (502.0)

1.00X10−7

168.6 (313.8)

0.0001

151.1 (731.5)

0.1945

293.0 (687.4)

8.64X10−6

195.1 (601.9)

7.21X10−7

95.0 (523.1)

ACPA IgG, U/ml (SD)

363.8 (776.1)

0.5244

282.5 (302.2)

0.5943

415.7 (962.9)

0.6334

306.4 (388.6)

0.5285

445.6 (400.6)

0.0033

350.8 (589.1)

0.1439

270.7 (308.3)

ACPA IgA, U/ml (SD)

11.8 (42.7)

0.0159

8.5 (21.4)

0.0198

14.0 (52.3)

0.1172

9.2 (34.4)

0.0468

14.0 (29.7)

0.0020

11.0 (37.6)

0.0015

4.1 (6.7)

ACPA sc, U/ml (SD)

8.6 (25.1)

0.0003

5.4 (9.3)

0.0136

10.7 (31.5)

0.0017

4.6 (12.1)

0.0999

7.9 (8.6)

3.89X10−7

6.8 (18.7)

3.05X10−5

2.3 (3.4)

Anti-CarPAb, U/ml (SD)

0.042 (0.285)

1.04X10−11

0.012 (0.016)

1.22X10−9

0.063 (0.367)

1.02X10−7

0.004 (0.012)

0.7585

0.010 (0.032)

0.1229

0.021 (0.189)

4.75X10−5

0.003 (0.011)

  1. ACPA Anti-citrullinated peptide antibody, AD Airway disease, CLD Chronic lung disease, CLD(+) with CLD, CLD(−) Without CLD, ILD Interstitial lung disease, NSIP, Nonspecific interstitial pneumonia, RF Rheumatoid factor, RA Rheumatoid arthritis, SC Secretory component, UIP Usual interstitial pneumonia
  2. The ILD group includes the UIP and NSIP groups. The CLD(+) group includes the UIP, NSIP, AD, and emphysema groups
  3. Data are presented as the mean value of each group; standard deviations are shown in parentheses
  4. Statistical difference was tested in comparison with the CLD(−) population using the Mann–Whitney U test