Clinical validation of the use of prototype software for automatic cartilage segmentation to quantify knee cartilage in volunteers

Zhang, Ping; Zhang, Ran Xu; Chen, Xiao Shuai; Zhou, Xiao Yue; Raithel, Esther; Cui, Jian Ling; Zhao, Jian

doi:10.1186/s12891-021-04973-4

Table 2 The cartilage mean T2* value ± standard deviation (SD) and regional differences between the automatic segmentation and manual correction based on automatic segmentation in different groups by articular effusion and cartilage degeneration

From: Clinical validation of the use of prototype software for automatic cartilage segmentation to quantify knee cartilage in volunteers

Subregion		ALL(n = 32)		No hydrarthrosis(n = 14)		Hydrarthrosis(n = 18)		WORMS 0 (n = 21)		WORMS 1–2 (n = 11)
Subregion		Mean ± SD (ms)	P	Mean ± SD (ms)	P	Mean ± SD (ms)	P	Mean ± SD (ms)	P	Mean ± SD (ms)	P
FMP	A	26.58 ± 2.94		27.73 ± 2.77		25.68 ± 2.83		26.37 ± 3.15		26.97 ± 2.59
FMP	M	26.58 ± 2.95		27.73 ± 2.77		25.68 ± 2.83		26.37 ± 3.15		26.97 ± 2.59
FMC	A	27.06 ± 3.60	0.001	26.20 ± 2.55	0.008	27.72 ± 4.20	0.001	26.85 ± 3.51	0.001	27.45 ± 3.93	0.012
FMC	M	26.58 ± 3.66	0.001	25.62 ± 2.78	0.008	27.32 ± 4.14	0.001	26.19 ± 3.54	0.001	27.31 ± 3.93	0.012
FMA	A	26.33 ± 4.44	0.001	24.77 ± 4.46	0.001	27.55 ± 4.15	0.001	27.04 ± 3.83	0.001	24.98 ± 5.37	0.005
FMA	M	25.39 ± 3.97	0.001	24.10 ± 4.33	0.001	26.39 ± 3.46	0.001	25.92 ± 3.23	0.001	24.37 ± 5.13	0.005
FTM	A	27.89 ± 5.30	0.003	26.00 ± 2.45	0.028	29.35 ± 6.43	0.046	25.89 ± 2.38	0.008	31.71 ± 7.15	0.285
FTM	M	27.81 ± 5.31	0.003	25.95 ± 2.47	0.028	29.26 ± 6.45	0.046	25.78 ± 2.32	0.008	31.68 ± 7.17	0.285
FTC	A	35.83 ± 14.93	0.001	30.37 ± 4.41	0.002	40.07 ± 18.65	0.001	31.90 ± 4.04	0.001	43.33 ± 23.74	0.008
FTC	M	31.98 ± 6.54	0.001	29.09 ± 3.33	0.002	34.23 ± 7.56	0.001	30.20 ± 2.87	0.001	35.38 ± 9.82	0.008
FTL	A	32.57 ± 7.13	0.001	32.85 ± 6.79	0.002	32.35 ± 7.57	0.001	31.50 ± 6.20	0.001	34.61 ± 8.59	0.008
FTL	M	29.73 ± 3.38	0.001	29.24 ± 1.71	0.002	30.10 ± 4.28	0.001	28.70 ± 2.40	0.001	31.69 ± 4.17	0.008
FLP	A	24.79 ± 2.88		24.72 ± 3.19		24.84 ± 2.70		24.86 ± 2.98		24.65 ± 2.79
FLP	M	24.79 ± 2.88		24.73 ± 3.19		24.84 ± 2.70		24.86 ± 2.98		24.65 ± 2.79
FLC	A	28.65 ± 4.02	0.109	27.77 ± 4.44	0.109	29.34 ± 3.63		27.70 ± 3.29	0.109	30.47 ± 4.78
FLC	M	28.64 ± 4.01	0.109	27.74 ± 4.4	0.109	29.34 ± 3.63		27.69 ± 3.27	0.109	30.47 ± 4.78
FLA	A	26.67 ± 5.56	0.018	26.15 ± 6.28	0.109	27.07 ± 5.09	0.068	26.55 ± 5.53	0.043	26.89 ± 5.88	0.180
FLA	M	26.57 ± 5.57	0.018	26.09 ± 6.30	0.109	26.95 ± 5.09	0.068	26.44 ± 5.54	0.043	26.84 ± 5.91	0.180
PLI	A	29.56 ± 19.81	0.001	22.92 ± 5.69	0.049	34.72 ± 25.02	0.008	23.97 ± 4.39	0.008	40.23 ± 31.41	0.049
PLI	M	23.86 ± 5.22	0.001	22.40 ± 5.64	0.049	25.00 ± 4.71	0.008	23.42 ± 4.48	0.008	24.70 ± 6.43	0.049
PLC	A	25.52 ± 5.47	0.001	24.47 ± 5.21	0.002	26.34 ± 5.67	0.001	25.30 ± 4.35	0.001	27.85 ± 6.77	0.008
PLC	M	23.97 ± 4.31	0.001	22.87 ± 3.93	0.002	24.82 ± 4.51	0.001	22.97 ± 3.51	0.001	25.88 ± 5.18	0.008
PLS	A	23.11 ± 4.13	0.317	22.30 ± 3.22		23.74 ± 4.71	0.317	22.61 ± 4.24	0.317	24.05 ± 3.91
PLS	M	23.10 ± 4.12	0.317	22.30 ± 3.22		23.72 ± 4.70	0.317	22.60 ± 4.23	0.317	24.05 ± 3.91
PMI	A	30.15 ± 6.90	0.001	28.06 ± 6.26	0.001	31.77 ± 7.10	0.001	29.86 ± 6.34	0.001	30.68 ± 8.17	0.005
PMI	M	27.21 ± 4.66	0.001	25.74 ± 4.21	0.001	28.35 ± 4.79	0.001	26.95 ± 4.78	0.001	27.70 ± 4.61	0.005
PMC	A	32.67 ± 7.02	0.001	30.59 ± 6.19	0.001	34.287.36	0.001	32.30 ± 7.26	0.001	33.37 ± 6.81	0.008
PMC	M	30.13 ± 4.94	0.001	29.68 ± 6.24	0.001	30.48 ± 3.81	0.001	29.11 ± 3.80	0.001	32.07 ± 6.38	0.008
PMS	A	26.68 ± 6.17	0.001	27.57 ± 5.46	0.028	25.98 ± 6.74	0.001	26.35 ± 6.16	0.002	27.30 ± 6.44	0.018
PMS	M	25.54 ± 4.80	0.001	26.61 ± 5.66	0.028	24.71 ± 3.99	0.001	24.87 ± 3.84	0.002	26.83 ± 6.27	0.018
TLP	A	23.10 ± 2.50		22.33 ± 2.02		23.69 ± 2.73		22.37 ± 2.29		24.49 ± 2.39
TLP	M	23.10 ± 2.50		22.33 ± 2.02		23.69 ± 2.73		22.37 ± 2.29		24.49 ± 2.39
TLC	A	20.84 ± 3.05	0.046	21.96 ± 2.86	0.285	19.98 ± 2.98	0.109	20.65 ± 3.24	0.043	21.20 ± 2.76	0.317
TLC	M	20.77 ± 2.96	0.046	21.90 ± 2.76	0.285	19.88 ± 2.87	0.109	20.54 ± 3.09	0.043	21.20 ± 2.76	0.317
TLA	A	24.75 ± 7.27	0.180	24.09 ± 5.98		25.26 ± 8.28	0.18	23.04 ± 4.88	0.317	28.01 ± 9.93	0.317
TLA	M	24.32 ± 6.14	0.180	24.09 ± 5.98		24.49 ± 6.42	0.18	22.84 ± 4.68	0.317	27.14 ± 7.72	0.317
TMP	A	18.77 ± 2.34	0.001	17.88 ± 2.03	0.013	19.47 ± 2.39	0.009	18.13 ± 1.88	0.001	20.00 ± 2.72	0.18
TMP	M	18.63 ± 2.34	0.001	17.80 ± 1.97	0.013	19.28 ± 2.44	0.009	17.94 ± 1.85	0.001	19.94 ± 2.68	0.18
TMC	A	19.51 ± 3.74	0.001	20.28 ± 4.01	0.001	18.91 ± 3.51	0.001	18.65 ± 3.06	0.001	21.16 ± 4.49	0.011
TMC	M	18.63 ± 2.34	0.001	19.20 ± 1.90	0.001	18.58 ± 3.34	0.001	18.25 ± 2.76	0.001	19.99 ± 2.55	0.011
TMA	A	23.93 ± 6.56	0.001	25.10 ± 8.07	0.002	23.01 ± 5.17	0.002	23.50 ± 7.36	0.001	24.73 ± 4.91	0.012
TMA	M	21.86 ± 5.32	0.001	22.28 ± 6.80	0.002	21.53 ± 3.99	0.002	21.35 ± 5.50	0.001	22.82 ± 5.05	0.012
T	A	21.82 ± 5.13	0.001	21.94 ± 5.16	0.001	21.72 ± 5.13	0.001	21.06 ± 4.63	0.001	23.26 ± 5.73	0.001
T	M	21.25 ± 4.43	0.001	21.27 ± 4.51	0.001	21.24 ± 4.39	0.001	20.55 ± 4.01	0.001	22.60 ± 4.90	0.001

A Automatic cartilage segmentation group, M Manual correction based on automatic segmentation group, T Total cartilage, FMP Femoral medial posterior, FMC Femoral medial central, FMA Femoral medial anterior, FTM Femoral trochlea medial, FTC Femoral trochlea central, FTL Femoral trochlea lateral, FLP Femoral lateral posterior, FLC Femoral lateral central, FLA Femoral lateral anterior, PLI Patellar lateral inferior, PLC Patellar lateral central, PLS Patellar lateral superior, PMI Patellar medial inferior, PMC Patellar medial central, PMS Patellar medial superior, TLP Tibial lateral posterior, TLC Tibial lateral central, TLA Tibial lateral anterior, TMP Tibial medial posterior, TMC Tibial medial central, TMA Tibial medial anterior

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ISSN: 1471-2474

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