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Table 2 The cartilage mean T2* value ± standard deviation (SD) and regional differences between the automatic segmentation and manual correction based on automatic segmentation in different groups by articular effusion and cartilage degeneration

From: Clinical validation of the use of prototype software for automatic cartilage segmentation to quantify knee cartilage in volunteers

Subregion ALL(n = 32) No hydrarthrosis(n = 14) Hydrarthrosis(n = 18) WORMS 0 (n = 21) WORMS 1–2 (n = 11)
Mean ± SD (ms) P Mean ± SD (ms) P Mean ± SD (ms) P Mean ± SD (ms) P Mean ± SD (ms) P
FMP A 26.58 ± 2.94   27.73 ± 2.77   25.68 ± 2.83   26.37 ± 3.15   26.97 ± 2.59  
M 26.58 ± 2.95 27.73 ± 2.77 25.68 ± 2.83 26.37 ± 3.15 26.97 ± 2.59
FMC A 27.06 ± 3.60 0.001 26.20 ± 2.55 0.008 27.72 ± 4.20 0.001 26.85 ± 3.51 0.001 27.45 ± 3.93 0.012
M 26.58 ± 3.66 25.62 ± 2.78 27.32 ± 4.14 26.19 ± 3.54 27.31 ± 3.93
FMA A 26.33 ± 4.44 0.001 24.77 ± 4.46 0.001 27.55 ± 4.15 0.001 27.04 ± 3.83 0.001 24.98 ± 5.37 0.005
M 25.39 ± 3.97 24.10 ± 4.33 26.39 ± 3.46 25.92 ± 3.23 24.37 ± 5.13
FTM A 27.89 ± 5.30 0.003 26.00 ± 2.45 0.028 29.35 ± 6.43 0.046 25.89 ± 2.38 0.008 31.71 ± 7.15 0.285
M 27.81 ± 5.31 25.95 ± 2.47 29.26 ± 6.45 25.78 ± 2.32 31.68 ± 7.17
FTC A 35.83 ± 14.93 0.001 30.37 ± 4.41 0.002 40.07 ± 18.65 0.001 31.90 ± 4.04 0.001 43.33 ± 23.74 0.008
M 31.98 ± 6.54 29.09 ± 3.33 34.23 ± 7.56 30.20 ± 2.87 35.38 ± 9.82
FTL A 32.57 ± 7.13 0.001 32.85 ± 6.79 0.002 32.35 ± 7.57 0.001 31.50 ± 6.20 0.001 34.61 ± 8.59 0.008
M 29.73 ± 3.38 29.24 ± 1.71 30.10 ± 4.28 28.70 ± 2.40 31.69 ± 4.17
FLP A 24.79 ± 2.88   24.72 ± 3.19   24.84 ± 2.70   24.86 ± 2.98   24.65 ± 2.79  
M 24.79 ± 2.88 24.73 ± 3.19 24.84 ± 2.70 24.86 ± 2.98 24.65 ± 2.79
FLC A 28.65 ± 4.02 0.109 27.77 ± 4.44 0.109 29.34 ± 3.63   27.70 ± 3.29 0.109 30.47 ± 4.78  
M 28.64 ± 4.01 27.74 ± 4.4 29.34 ± 3.63 27.69 ± 3.27 30.47 ± 4.78
FLA A 26.67 ± 5.56 0.018 26.15 ± 6.28 0.109 27.07 ± 5.09 0.068 26.55 ± 5.53 0.043 26.89 ± 5.88 0.180
M 26.57 ± 5.57 26.09 ± 6.30 26.95 ± 5.09 26.44 ± 5.54 26.84 ± 5.91
PLI A 29.56 ± 19.81 0.001 22.92 ± 5.69 0.049 34.72 ± 25.02 0.008 23.97 ± 4.39 0.008 40.23 ± 31.41 0.049
M 23.86 ± 5.22 22.40 ± 5.64 25.00 ± 4.71 23.42 ± 4.48 24.70 ± 6.43
PLC A 25.52 ± 5.47 0.001 24.47 ± 5.21 0.002 26.34 ± 5.67 0.001 25.30 ± 4.35 0.001 27.85 ± 6.77 0.008
M 23.97 ± 4.31 22.87 ± 3.93 24.82 ± 4.51 22.97 ± 3.51 25.88 ± 5.18
PLS A 23.11 ± 4.13 0.317 22.30 ± 3.22   23.74 ± 4.71 0.317 22.61 ± 4.24 0.317 24.05 ± 3.91  
M 23.10 ± 4.12 22.30 ± 3.22 23.72 ± 4.70 22.60 ± 4.23 24.05 ± 3.91
PMI A 30.15 ± 6.90 0.001 28.06 ± 6.26 0.001 31.77 ± 7.10 0.001 29.86 ± 6.34 0.001 30.68 ± 8.17 0.005
M 27.21 ± 4.66 25.74 ± 4.21 28.35 ± 4.79 26.95 ± 4.78 27.70 ± 4.61
PMC A 32.67 ± 7.02 0.001 30.59 ± 6.19 0.001 34.287.36 0.001 32.30 ± 7.26 0.001 33.37 ± 6.81 0.008
M 30.13 ± 4.94 29.68 ± 6.24 30.48 ± 3.81 29.11 ± 3.80 32.07 ± 6.38
PMS A 26.68 ± 6.17 0.001 27.57 ± 5.46 0.028 25.98 ± 6.74 0.001 26.35 ± 6.16 0.002 27.30 ± 6.44 0.018
M 25.54 ± 4.80 26.61 ± 5.66 24.71 ± 3.99 24.87 ± 3.84 26.83 ± 6.27
TLP A 23.10 ± 2.50   22.33 ± 2.02   23.69 ± 2.73   22.37 ± 2.29   24.49 ± 2.39  
M 23.10 ± 2.50 22.33 ± 2.02 23.69 ± 2.73 22.37 ± 2.29 24.49 ± 2.39
TLC A 20.84 ± 3.05 0.046 21.96 ± 2.86 0.285 19.98 ± 2.98 0.109 20.65 ± 3.24 0.043 21.20 ± 2.76 0.317
M 20.77 ± 2.96 21.90 ± 2.76 19.88 ± 2.87 20.54 ± 3.09 21.20 ± 2.76
TLA A 24.75 ± 7.27 0.180 24.09 ± 5.98   25.26 ± 8.28 0.18 23.04 ± 4.88 0.317 28.01 ± 9.93 0.317
M 24.32 ± 6.14 24.09 ± 5.98 24.49 ± 6.42 22.84 ± 4.68 27.14 ± 7.72
TMP A 18.77 ± 2.34 0.001 17.88 ± 2.03 0.013 19.47 ± 2.39 0.009 18.13 ± 1.88 0.001 20.00 ± 2.72 0.18
M 18.63 ± 2.34 17.80 ± 1.97 19.28 ± 2.44 17.94 ± 1.85 19.94 ± 2.68
TMC A 19.51 ± 3.74 0.001 20.28 ± 4.01 0.001 18.91 ± 3.51 0.001 18.65 ± 3.06 0.001 21.16 ± 4.49 0.011
M 18.63 ± 2.34 19.20 ± 1.90 18.58 ± 3.34 18.25 ± 2.76 19.99 ± 2.55
TMA A 23.93 ± 6.56 0.001 25.10 ± 8.07 0.002 23.01 ± 5.17 0.002 23.50 ± 7.36 0.001 24.73 ± 4.91 0.012
M 21.86 ± 5.32 22.28 ± 6.80 21.53 ± 3.99 21.35 ± 5.50 22.82 ± 5.05
T A 21.82 ± 5.13 0.001 21.94 ± 5.16 0.001 21.72 ± 5.13 0.001 21.06 ± 4.63 0.001 23.26 ± 5.73 0.001
M 21.25 ± 4.43 21.27 ± 4.51 21.24 ± 4.39 20.55 ± 4.01 22.60 ± 4.90
  1. A Automatic cartilage segmentation group, M Manual correction based on automatic segmentation group, T Total cartilage, FMP Femoral medial posterior, FMC Femoral medial central, FMA Femoral medial anterior, FTM Femoral trochlea medial, FTC Femoral trochlea central, FTL Femoral trochlea lateral, FLP Femoral lateral posterior, FLC Femoral lateral central, FLA Femoral lateral anterior, PLI Patellar lateral inferior, PLC Patellar lateral central, PLS Patellar lateral superior, PMI Patellar medial inferior, PMC Patellar medial central, PMS Patellar medial superior, TLP Tibial lateral posterior, TLC Tibial lateral central, TLA Tibial lateral anterior, TMP Tibial medial posterior, TMC Tibial medial central, TMA Tibial medial anterior