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Table 1 Results of BMD measured by DXA, vBMD of cortical bone, and cortical width measured by μCT

From: Sweep imaging with Fourier transform as a tool with MRI for evaluating the effect of teriparatide on cortical bone formation in an ovariectomized rat model

 

Time after the initiation of treatment

Non-TPTD

TPTD

P-value

DXA

 BMD (mg/cm2)

4 weeks

89.7 ± 4.3

99.9 ± 4.0

< 0.01

12 weeks

98.1 ± 3.0

104.4 ± 5.0

< 0.01

24 weeks

85.3 ± 2.1

95.3 ± 5.2

< 0.05

μCT

 vBMD of cortical bone (mg/cm3)

4 weeks

1190 ± 112

1229 ± 71

0.67

12 weeks

1237 ± 49

1231 ± 93

0.94

24 weeks

1223 ± 67

1235 ± 84

0.82

 Cortical width (μm)

4 weeks

709 ± 16

760 ± 15

< 0.01

12 weeks

723 ± 13

786 ± 15

< 0.01

24 weeks

714 ± 22

801 ± 26

< 0.01

  1. Values are expressed as means ± standard deviations. BMD Bone mineral density, DXA Dual-energy X-ray absorptiometry, vBMD Volumetric bone mineral density, μCT Microcomputed tomography, TPTD Teriparatide