Skip to main content

Table 4 Intergroup comparisons of clinical and radiographic parameters between OP group, osteopenia group and normal group

From: The correlation between volumetric bone mineral density and morphological parameters of the proximal femur and clinical outcomes in ankylosing spondylitis patients with hip involvement

Characteristics OP group (n = 8) Osteopenia group (n = 28) Normal group (n = 29) P value
BMI 22.4 ± 4.3 (17.3–28.5) 25.5 ± 4.8 (16.6–39.5) 27.0 ± 4.3 (17.5–38.9) 0.040
Male gender, n (%) 8 (100%) 25 (89.3%) 23 (79.3%) 0.271
Age at outpatient visit (years) 28.3 ± 12.5 (17–54) 35.3 ± 8.8 (21–54) 32.9 ± 7.9 (21–54) 0.143
Age at onset (years) 18.5 ± 3.8 (14–24) 23.0 ± 5.9 (15–38) 25.0 ± 6.1 (15–39) 0.021
Duration of AS (years) 10.0 ± 12.7 (0–37.0) 12.5 ± 10.5 (0.5–37.0) 8.1 ± 6.8 (0–22.0) 0.214
Diagnosis delay (years) 4.6 ± 6.8 (0.0–18.0) 6.11 ± 7.23 (0–27.0) 5.3 ± 7.4 (0–33.0) 0.855
EAMs, n (%)
 Uveitis 0 2 (7.1%) 2 (6.9%) 0.744
 IBD 0 2 (7.1%) 2 (6.9%) 0.744
 Family history, n (%) 3 (37.5%) 7 (25.0%) 4 (13.8%) 0.302
 HLA-B27 positivity, n (%) 8 (100%) 26 (92.9%) 27 (93.1%) 0.744
 Current use of NSAIDs, n (%) 5 (62.5%) 16 (57.1%) 22 (75.9%) 0.325
 Current use of DMARDs, n (%) 5 (62.5%) 12 (42.9%) 18 (62.1%) 0.308
 ESR (mm) 30.9 ± 21.2 (2–65) 35.8 ± 21.6 (3–93) 28.3 ± 18 (8–91) 0.383
 CRP (mg/L) 19.2 ± 10.9 (3.5–35.2) 33.4 ± 32.9 (3.2–133.0) 22.5 ± 22.8 (1.9–100.0) 0.222
 hsCRP (mg/L) 16.8 ± 13.2 (0.1–34.2) 31.9 ± 34.9 (0.8–137.4) 21.8 ± 24.2 (0.2–114.6) 0.277
 BASDAI 3.9 ± 1.8 (1.4–5.8) 4.3 ± 2.0 (0.6–8.4) 3.1 ± 2.1 (0.4–7.8) 0.094
 BASFI 2.4 ± 1.7 (0.5–5.5) 2.4 ± 1.7 (0.3–6.3) 1.8 ± 1.3 (0.2–4.0) 0.269
 SF-12 PCS 35.1 ± 15.5 (16.5–58.4) 34.9 ± 11.6 (18.2–55.4) 40.7 ± 11.0 (18.5–55.9) 0.158
 SF-12 MCS 36.1 ± 15.9 (17.1–55.4) 37.4 ± 11.6 (20.3–57.9) 42.2 ± 10.0 (21.4–55.9) 0.197
 ASQOL 7.5 ± 5.9 (2–17) 7.0 ± 4.2 (1–16) 5.5 ± 4.2 (0–14) 0.344
 HHS 72.5 ± 27.9 (24–100) 68.6 ± 20.8 (36–100) 83.6 ± 13.1 (48–99) 0.013
 BASRI-Hip 1.9 ± 1.3 (0–3) 2.5–1.3 (0–4) 1.2 ± 1.2 (0–4) 0.002
 CFI 3.4 ± 1.0 (1.7–4.8) 3.5 ± 0.9 (2.2–5.8) 3.6 ± 0.7 (2.1–5.0) 0.763
 MCFI 2.1 ± 0.3 (1.8–2.7) 2.2 ± 0.2 (1.8–2.6) 2.2 ± 0.3 (1.3–3.0) 0.766
 CBR 0.4 ± 0.1 (0.3–0.6) 0.5 ± 0.1 (0.3–0.7) 0.4 ± 0.1 (0.3–0.6) 0.094
 CCR 0.5 ± 0.2 (0.36–0.9) 0.5 ± 0.1 (0.3–0.8) 0.5 ± 0.1 (0.3–0.7) 0.768
  1. The value of continuous variables was presented as mean ± standard deviation and the categorical variables were based on presented as number plus percentage
  2. Abbreviations: OP Osteoporosis, BMI Body mass index, AS Ankylosing spondylitis, EAMs Extra-articular manifestations, IBD Inflammatory bowel disease, NSAIDs Nonsteroidal anti-inflammatory drugs, DMARDs Disease modifying antirheumatic drugs, ESR Erythrocyte sedimentation rate, CRP C reactive protein, hsCRP High sensitive C reactive protein, BASDAI Bath ankylosing spondylitis disease activity index, BASFI Bath ankylosing spondylitis functional index, SF-12 PCS Short form-12 physical component summary, SF-12 MCS Short form-12 mental component summary, ASQOL Ankylosing spondylitis quality of life, HHS Harris hip score, BASRI-Hip The bath ankylosing spondylitis radiology hip index