Skip to main content

Table 3 Top 10 hub genes of the significantly up-regulated and down-regulated DEMs in the PPI network ranked by MCC

From: Identification of transcription factors and construction of a novel miRNA regulatory network in primary osteoarthritis by integrated analysis

ID

Down-regulated DEMs

Up-regulated DEMs

Gene Symbol

Score

Gene Symbol

Score

1

KRAS

253

NR3C1

23

2

NRAS

237

PPARGC1A

22

3

CDC42

132

SUMO1

17

4

GDNF

119

MEF2C

15

5

SOS1

92

FOXO3

12

6

PIK3R3

79

PPP1CB

12

7

GSK3B

72

MAP2K1

12

8

IRS2

58

RARA

10

9

GNG12

57

RHOC

9

10

PRKCA

42

CDC23

9

11

  

CREB3L2

9

  1. DEMs differentially expressed microRNAs
Back to article page

BMC Musculoskeletal Disorders

ISSN: 1471-2474

Contact us