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Table 1 Summary of treatment groups

From: Trend of serum C-reactive protein is associated with treatment outcome of hip Periprosthetic joint infection undergoing two-stage exchange arthroplasty: a case control study

 

Treatment success (n = 67)

Treatment failure (n = 7)

p

Age (years)a

58.6 ± 12.7

49.6 ± 14.5

0.034*

Female (%)

26 (38.8)

0 (0)

0.047*

BMI (kg/m2)a

25.9 (24.0–27.8)

30.1 (28.5–31.7)

0.102

CCI ≥ 4 (%)

29 (42.6)

3 (50)

0.995

Sinus discharge (%)

16 (23.9)

3 (42.9)

0.363

Chronic PJI (%)

44 (65.7)

6 (85.7)

0.416

Interim period (weeks)

13.0 (12.0–15.6)

13.0 (10.0–20.0)

0.572

2nd-stage surgery time (hours)

2.4 (1.9–3.1)

3.1 (2.4–4.1)

0.102

2nd-stage blood loss (mL)

975 (725–1625)

2200 (1000–2300)

0.056

Pre-resection CRPb

29.9 (14.8–74.1)

41.3 (9.5–102.1)

0.737

ΔCRPb

22.1 (10.5–62.7)

18.8 (6.1–48.2)

0.747

ΔCRP/pre-resection CRPb

0.85 (0.63–0.95)

0.64 (0.28–0.84)

0.278

Pre-reimplantation CRPb

3.6 (1.8–7.3)

20.2 (10.4–33.6)

0.008*

CRP decrease ratiob

 1st vs. 2nd week

47.7 (35.8–67.1)

42.8 (−18.1–55.7)

0.477

 2nd vs. 3rd week

40.0 (15.1–68.1)

27.1 (−2.5–52.1)

0.832

 1st vs. 3rd week

75.3 (55.1–85.9)

48.7 (3.9–0.7)

0.323

Pathogen

 No growth

24 (35.8)

0 (0)

 MRSA

4 (5.9)

2 (28.6)

0.046*

 MSSA

20 (29.9)

2 (28.6)

0.939

 Other G(+)

8 (11.9)

2 (28.6)

0.245

 G(−)

5 (7.5)

1 (14.3)

 Fungus, mycobacteria

3 (4.5)

0 (0)

 Polymicrobial

3 (4.5)

0 (0)

  1. aResults are expressed as mean ± standard deviation
  2. bResults are expressed as median (interquartile range)
  3. * p < 0.05
  4. Abbreviations: BMI body mass index, CCI Charlson Comorbidity Index, CRP C-reactive protein, G(+) gram positive, G(−) gram negative, MRSA methicillin-resistant Staphylococcus aureus, MSSA methicillin-sensitive Staphylococcus, PJI periprosthetic joint infection