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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: Osteoclasts secrete leukemia inhibitory factor to promote abnormal bone remodeling of subchondral bone in osteoarthritis

Fig. 3

(A) micro-CT images of sagittal views of the subchondral bone medial compartment at 4 weeks and 8 weeks after the sham operation or ACLT surgery. (B − D) Quantitative analysis of micro-CT parameters of the tibial subchondral bone: bone volume fraction (BV/TV) (B), subchondral bone plate thickness (SBP.Th) (C) and trabecular separation (Tb.Sp)(D). Vehicle = ACLT surgery treated with vehicle. ALN = ACLT surgery treated with alendronate. Numerical data are presented as means ± SD; **p < 0.01 compared to the sham group, ##p < 0.01 compared to the vehicle group

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