Author, Year, Country | Follow-up | Participants | Outcome measurement | Number of cases | Adjustment | Main findings 25(OH)D nmol/l; OR/RR/HR; 95% CI |
---|---|---|---|---|---|---|
Konstari, 2012, Finland [10] | 22-23 years | 805 Finnish adults from the Mini-Finland Health Examination Survey Age: ≥30 years 55.3% women | Hip OA was defined by -documented history of previously diagnosed hip OA -hip arthroplasty due to OA | 17 men and 23 women | age, gender, education, BMI, physical workload, smoking, leisure time physical activity, injuries, and season of blood draw | Q1 (13-33): reference Q2 (34-43): 1.22; 0.46-3.21 Q3 (44-56): 1.15; 0.43-3.04 Q4 (57-180): 0.72; 0.24-2.13 P for trend: 0.23 |
Konstari, 2014, Finland [9] | 10 years | 5274 adults living in mainland Finland from the Health 2000 Survey Age ≥ 30 years 54.1% women | Incidence of hip OA was drawn from the National Health Care Register using International Classification of Diseases, 10th revision (ICD-10) | 45 participants | Age, gender, BMI, current physical workload, education, smoking, leisure time physical activity, time of serum collection, injuries and difficulty in walking due to discomfort or trouble in the knee or hip | Q1 (0-33): reference Q2 (34-42): 2.23; 0.76-6.55 Q3 (43-54): 2.96; 1.07-8.21 Q4 (55-134): 2.81; 1.01-7.85 P for trend 0.053 |
Hussain, 2015, Australia [8] | 9.1 ± 2.7 years | 9135 participants from the Australian Diabetes, Obesity and Lifestyle Study including population representative of Australia Age: ≥40 years 54.3% women | Incidence of hip replacement for OA by linking cohort records to the Australian Orthopaedic Association National Joint Replacement Registry | 90 men and 111 women | Age, BMI, ethnicity, smoking status, physical activity, season of blood collection, latitude, hypertension, diabetes, and Area-level disadvantage. | Men Q1 (≤51): reference Q2 (52-65): 2.02; 1.01-4.06 Q3 (66-81): 2.17; 1.08-4.06 Q4 (≥82): 2.30; 1.09-4.82 P for trend 0.04 Women Q1 (≤41): reference Q2 (42-54): 1.21; 0.70-2.09 Q3 (55-69): 1.08; 0.61-1.91 Q4 (≥70): 1.29; 0.71-2.34 P for trend 0.49 |