Fig. 3From: Rolipram plays an anti-fibrotic effect in ligamentum flavum fibroblasts by inhibiting the activation of ERK1/2Inhibiting PDE4 with Rolipram attenuates Col I and TGF-β1 expression levels in LF hypertrophy fibroblasts. Primary LF fibroblasts were treated with rolipram (50 nM) at different times. Western blot analysis shows the expression for Col I and TGF-β1 in LF fibroblasts treated with Rolipram. GAPDH served as an endogenous control. **P < 0.01Back to article page