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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Rolipram plays an anti-fibrotic effect in ligamentum flavum fibroblasts by inhibiting the activation of ERK1/2

Fig. 1

The expression of PDE4A and 4B in hypertrophic fibroblasts is up-regulated. A Heatmap of differentially expressed PDEs. Data shown is mRNA expression levels of LF samples using qRT-PCR. The shade of the color in the figure represents the △△Ct value of the qPCR result. LFH stands for LF hypertrophy group and NLFH represents the control group. B-E qRT-PCR analysis of PDE4A and PDE4B mRNA expression levels in the LFH versus the NLFH groups. Data are presented as the mean ± 95%CI. **p < 0.01. The mRNA expression of PDE4A and PDE4B were related to the thickness of LF. The correlation coefficient (R) and probability (P) value obtained by regression analysis are shown in the figure

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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