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Table 1 Patients characteristics stratified for gender

From: Influence of IGF-I serum concentration on muscular regeneration capacity in patients with sarcopenia

 

Total sample

n = 31

Female

n = 20

Male

n = 11

p-Value

Age [years]

80.6 (7.4)

79.6 (8.4)

82.5 (5.2)

0.306

Handgrip strength [kg]

23.2 (8.9)

20.6 (6.9)

27.8 (10.6)

0.030

SMI [kg/m2]

6.9 (1.2)

6.7 (1.2)

7.3 (1.3)

0.163

z-score sarcopenia

−1.2 (1.8)

−1.7 (1.6)

−0.3 (1.9)

0.040

IGF-I [ng/ml]

64.1 (25.6)

67.8 (25.0)

57.5 (26.7)

0.296

IGFBP-3 [ng/ml]

1577 (544)

1729 (542)

1300 (446)

0.033

ALS [mU/ml]

259 (131)

301 (126)

182 (104)

0.013

MUNIX

95 (43)

107 (43)

72 (33)

0.032

MUSIX [μV]

87 (35)

77 (18)

106 (51)

0.030

Ki67+ myocytes [%]

48.6 (17.9)

50.0 (18.2)

46.3 (18.0)

0.600

NCAM+ fibers [%]

1.1 (1.6)

1.1 (1.8)

1.0 (1.2)

0.797

  1. Mean (SD) unless stated otherwise. Two patients did not tolerate the MUNIX procedure. Two missing measurements for Ki67 staining and 1 missing for NCAM expression due to insufficient antibody binding. SMI Skeletal muscle index, IGF-I Insulin-like growth factor 1, IGFBP-3 Insulin-like growth factor binding protein 3, ALS Acid labile subunit, MUNIX Motor unit number index, MUSIX Motor unit size index, NCAM neural cell adhesion molecule. p-values between groups were calculated using two sample-t-test. p-Values <.05 are bold