Skip to main content

Table 2 Univariate analyses of variables associated with the magnitude of surgery-related trauma

From: Are postoperative NLR and PLR associated with the magnitude of surgery-related trauma in young and middle-aged patients with bicondylar tibial plateau fractures? A retrospective study

Variable

Total patients (n = 136)

Group 1 (n = 61)

Group 2 (n = 75)

P

Baseline characteristics of the patients

Sex (male), n (%)

97 (71.3)

47 (77.0)

50 (66.7)

0.183

Age (years), mean ± SD

45.6 ± 10.8

43.9 ± 10.7

47.1 ± 10.8

0.090

BMI (Kg/m^2), mean ± SD

26.2 ± 3.3

26.4 ± 3.2

26.0 ± 3.5

0.508

Tobacco consumption (yes), n (%)

31 (22.8)

17 (27.9)

14 (18.7)

0.203

Alcohol consumption (yes), n (%)

29 (21.3)

15 (24.6)

14 (18.7)

0.402

Hypertension (yes), n (%)

24 (17.6)

11 (18.0)

13 (17.3)

0.915

Diabetes (yes), n (%)

11 (8.1)

6 (9.8)

5 (6.7)

0.500

Living area, n (%)

Rural

Urban

87 (64.0)

49 (36.0)

35 (57.4)

26 (42.6)

52 (69.3)

23 (30.7)

0.149

Injury mechanisms (high energy), n (%)

111 (81.6)

48 (78.7)

63 (84.0)

0.426

Schatzker classification, n (%)

Type V

Type VI

68 (50.0)

68 (50.0)

29 (47.5)

32 (52.5)

39 (52.0)

36 (48.0)

0.605

Preoperative stay (days), n (%)

0–9 cutoff

≥ 10

106 (77.9)

30 (22.1)

51 (83.6)

10 (16.4)

55 (73.3)

20 (26.7)

0.151

Preoperative hematologic indicators

Neutrophil count (> 6.30 × 10^9/L, reference), n (%)

77 (56.6)

35 (57.4)

42 (56.0)

0.872

Lymphocyte count (< 1.10 × 10^9/L, reference), n (%)

28 (20.1)

9 (14.7)

19 (25.3)

0.129

PLT count (× 10^9/L), n (%)

125–350 reference

< 125

> 350

127 (93.4)

5 (3.7)

4 (2.9)

58 (95.1)

2 (3.3)

1 (1.6)

69 (92.0)

3 (4.0)

3 (4.0)

0.698

AST/ALT (> 1, reference), n (%)

67 (49.3)

31 (50.8)

36 (48.0)

0.744

WBC (> 10 × 10^9/L, reference), n (%)

44 (32.4)

17 (27.9)

27 (36.0)

0.313

NLR (> 5.9, cutoff), n (%)

45 (33.1)

16 (26.2)

29 (38.7)

0.125

PLR (> 137.5, cutoff), n (%)

68 (50.0)

28 (45.9)

40 (53.3)

0.389

ASA class, n (%)

I

II

III or above

13 (9.6)

110 (80.8)

13 (9.6)

7 (11.5)

51 (83.6)

3 (4.9)

6 (8.0)

59 (78.7)

10 (13.3)

0.221

RBC (< lower limit × 10^12/L, reference), n (%)

53 (39.0)

22 (36.1)

31 (41.3)

0.531

HGB (< lower limit × g/L, reference), n (%)

78 (57.4)

31 (50.8)

47 (62.7)

0.165

ALB (< 40 g/L, reference), n (%)

49 (36.0)

20 (32.8)

29 (38.7)

0.477

HCRP (> 16.1 mg/L, cutoff), n (%)

82 (60.3)

35 (57.4)

47 (62.7)

0.531

Intraoperative indexes

Anesthetization, n (%)

General

Intraspinal

87 (64.0)

49 (36.0)

44 (68.9)

17 (31.1)

45 (60.0)

30 (40.0)

0.285

Bone grafting (yes), n (%)

62 (45.6)

31 (50.8)

31 (41.3)

0.269

Operative time (minutes), n (%)

0-130 cutoff

> 130

61 (44.9)

75 (55.1)

45 (73.8)

16 (26.2)

16 (21.3)

59 (78.7)

< 0.001

Intraoperative tourniquet use (yes), n (%)

78 (57.4)

28 (45.9)

50 (66.7)

0.015

Intraoperative blood loss (> 330ml, cutoff), n (%)

54 (39.7)

13 (21.3)

41 (54.7)

< 0.001

Length of incision (cm), n (%)

0–19 cutoff

> 19.0

64 (47.1)

72 (52.9)

50 (82.0)

11 (18.0)

14 (18.7)

61 (81.3)

< 0.001

Hematologic indexes of the postoperative 1st day

Neutrophil count (> 6.30 × 10^9/L, reference), n (%)

119 (87.5)

50 (82.0)

69 (92.0)

0.078

Lymphocyte count (< 1.10 × 10^9/L, reference), n (%)

72 (52.9)

27 (44.3)

45 (60.0)

0.067

PLT count (× 10^9/L), n (%)

125–350 reference

< 125

> 350

105 (77.2)

5 (3.7)

26 (19.1)

45 (73.8)

4 (6.6)

12 (19.6)

60 (80.0)

1 (1.3)

14 (18.7)

0.261

WBC (> 10 × 10^9/L, reference), n (%)

88 (64.7)

38 (62.3)

50 (66.7)

0.596

NLR (> 10.1, cutoff), n (%)

48 (35.3)

15 (24.6)

33 (44.0)

0.018

PLR (> 223.9, cutoff), n (%)

83 (61.0)

27 (44.3)

56 (74.7)

0.001

RBC (< lower limit × 10^12/L, reference), n (%)

106 (77.9)

42 (68.9)

64 (85.3)

0.021

HGB (< lower limit × g/L, reference), n (%)

113 (83.1)

46 (77.0)

67 (88.0)

0.090

ALB (< 35 g/L, reference), n (%)

72 (52.9)

30 (49.2)

42 (56.0)

0.428

HCRP (> 47.6 mg/L, cutoff), n (%)

88 (64.7)

34 (55.7)

54 (72.0)

0.048

  1. Note: P value < 0.05 was considered statistically significant. Cutoff values are determined by ROC analysis. Abnormal reference range for RBC: male < 4 × 10^12/L and female < 3.5 × 10^12/L, for HGB: male < 130 g/L and female < 115 g/L. Abbreviations: BMI, body mass index; PLT, platelet; AST, aspartate aminotransferase; ALT, alanine transaminase; WBC, white blood cell; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; ASA, American Society of Anesthesiologists; RBC, red blood cell; HGB, hemoglobin; ALB, albumin; HCRP, hypersensitive C-reactive protein