Fig. 5
From: TGF-β3 regulates adhesion formation through the JNK/c-Jun pathway during flexor tendon healing
HE Staining and Collagen Type-III Immunohistochemistry Staining. (A) HE staining of healing tendon at given days. The yellow arrow indicates the loose and disordered arrangement of collagen fibers, the green arrow indicates the rupture of tendon tissue, and the blue arrow indicates the degeneration and necrosis of collagen fibers. Scale bars = 40 μm. (B) Immunohistochemistry of Collagen Type-III in Healing Flexor Tendon Tissues at Day 14, 21, and 28 post-repair. Scale bars = 40 μm. (C) Integral optical density (IOD) of Collagen Type-III level showed a significant decrease of ad-TGF-β3 treated group relative to vehicle group in Healing Flexor Tendon Tissues. *P < 0.05, vs. vehicle group. n = 6 for each group